Role of tumor-associated macrophages in tumor progression and invasion

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TGF-β and immune cells: an important regulatory axis in the tumor microenvironment and progression (2010, background): “The increased infiltration of myeloid cells into the invasive front of tumors, and their production of MMPs and TGFβ1 are found to be one of the major contributors to enhanced tumor invasion and metastasis due to deletion of TGF-β signaling in epithelial cells [9,53,56].”
Much More than M1 and M2 Macrophages, There are also CD169+ and TCR+ Macrophages (2015, methodology): “We thank the fellowship for LCG (207760), provided by the Consejo Nacional de Ciencia y Tecnología (CONACyT), Mexico, and the FNS (31-46833) and the Ligue Pulmonaire Genevoise.”
The tumor microenvironment. (2012, background): “For example, targeting macrophage activation or migration could serve as a way to block the infiltration of inflammatory cells that often precedes and leads to cancer formation [41].”
Dynamics of the immune reaction to pancreatic cancer from inception to invasion. (2007, neutral): “including tumor-associated macrophages (14), myeloid-derived”
Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability. (2009, background): “TAM assist tumor cell malignant behaviour in many ways by releasing cytokines, growth factors and matrix degrading enzymes [62-65] and a host of angiogenic factors (e.”