Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability.

By F. Colotta, P. Allavena, A. Sica, C. Garlanda, A. Mantovani. Carcinogenesis, 2009

2,856 citations recorded by the source corpus.

Subfields: Molecular Biology, Oncology

View Paper: https://www.semanticscholar.org/paper/2e2c9fb832accd928f8620b127b584298ecbabdc

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

1. M. Karin
2. P. Allavena
3. A. Mantovani
4. Herbert Levine
5. A. Marusyk
6. K. Polyak
7. José N. Onuchic
8. M. Qasim

In Oncology

1. M. Karin
2. A. Mantovani
3. P. Allavena
4. Y. Ben‐Neriah
5. G. Germano
6. A. Marusyk
7. K. Polyak
8. M. Hung

Citations in the corpus

• Deubiquitination and Stabilization of PD-L1 by CSN5 (2016, background): “Although the innate response of inflammation is critical for host immune defense, cancer cells often develop T cell resistance in the milieu of chronic inflammation, which is known as the seventh hallmark of cancer, facilitating angiogenesis, cancer cell progression, invasion, and metastasis (Colott”
• Review of the Isolation, Characterization, Biological Function, and Multifarious Therapeutic Approaches of Exosomes (2019, background): “Exosome-mediated inflammatory responses are involved in all stages of tumor development, immune surveillance, and resistance to therapy [184,185].”
• Hallmarks of cancer: the next generation. (2011, neutral): “Yet other distinct attributes of cancer cells have been proposed to be functionally important for the development of cancer andmight therefore be added to the list of core hallmarks (Negrini et al., 2010; Luo et al., 2009; Colotta et al., 2009).”
• Role of macrophage targeting in the antitumor activity of trabectedin. (2013, background): “C recognized as a hallmark of tumors (Colotta et al., 2009; Hanahan and Weinberg, 2011).”
• Cancer as a metabolic disease (2010, background): “inflammation, regardless of origin, damages tissue morphogenetic fields that eventually produce neoplastic cells [123,124,166].”
• Upsides and Downsides of Reactive Oxygen Species for Cancer: The Roles of Reactive Oxygen Species in Tumorigenesis, Prevention, and Therapy (2012, neutral): “Experimental and epidemiologic research over the past several years has indicated close associations between ROS, chronic inflammation, and cancer (62, 105, 106, 132, 209, 210, 259, 269, 326).”