Neurogenic radial glia in the outer subventricular zone of human neocortex

By David V. Hansen, Jan H. Lui, Philip R. L. Parker, A. Kriegstein. 2010

1,301 citations recorded by the source corpus.

Subfields: Cancer Research, Developmental Neuroscience, Molecular Biology

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Citations in the corpus

Brain Region-specific Organoids using Mini-bioreactors for Modeling ZIKV Exposure (2016, neutral): “We sometimes observed HOPX+ radially-oriented basal processes from these oRGCs with pial contact but lacking an apical process (Figure S3B), a hallmark of human oRGCs (Hansen et al., 2010) (Figure S3A).”
Brain organoids: advances, applications and challenges (2019, background): “Such cortical organoids have also attracted the most interest in the field because the cerebral cortex is the most unique and evolutionarily expanded region of the human brain, in comparison to that of other animals, and is often severely affected in many neurological disorders (Bystron et al., 2008”
The cell biology of neurogenesis: toward an understanding of the development and evolution of the neocortex. (2014, background): “…al. 2004, Noctor et al. 2004, Pilz et al. 2013), among BPs (Betizeau et al. 2013, Hansen et al. 2010), and from BPs to neurons (Attardo et al. 2008, Betizeau et al. 2013, Hansen et al. 2010, Haubensak et al. 2004, Wang et al. 2011). www.annualreviews.org • Cell Biology of Neurogenesis 473 A nn u.”
OSVZ progenitors of human and ferret neocortex are epithelial-like and expand by integrin signaling (2010, result): “, OSVZ progenitors can therefore be regarded as delaminated RGCs, a conclusion reported independentl”
Neural progenitors, neurogenesis and the evolution of the neocortex (2014, background): “By contrast, bRG differentiative (bIP-genic) divisions appear to be characteristic of primate bRG (Hansen et al., 2010; Betizeau et al., 2013), as theyoccur only rarely in the embryonic neocortex of mouse (Wang et al., 2011) and ferret (Gertz et al., 2014).”
Self-organization of axial polarity, inside-out layer pattern, and species-specific progenitor dynamics in human ES cell–derived neocortex (2013, background): “Moreover, the optimized culture generates species-specific progenitors in the outer subventricular zone (oSVZ), called outer radial glia (oRG), which are abundantly present in the human neocortex (11, 12) but rare in the mouse cortex (13, 14).”
Development and Evolution of the Human Neocortex (2011, neutral): “Increases in neocortical volume and surface area, particularly in the human, are related to the expansion of progenitor cells in the outer subventricular zone (OSVZ) during development (Smart et al., 2002; Hansen et al., 2010; Fietz et al., 2010).”
Molecular Identity of Human Outer Radial Glia During Cortical Development (2015, neutral): “In contrast, the OSVZ contains a more pure population of oRG cells that lack apical processes (Fietz et al., 2010; Hansen et al., 2010), although the morphology of these cells may also be dynamic and diverse (Betizeau et al., 2013; Gertz et al., 2014).”
Human cerebral cortex development from pluripotent stem cells to functional excitatory synapses (2012, background): “Although neuroepithelial ventricular zone cells are the primary stem and progenitor population of the cerebral cortex, at least two secondary progenitor cell populations, basal progenitor cells and outer radial glial cells (oRG), have been identified in mouse, ferret and human”
The Cellular and Molecular Landscapes of the Developing Human Central Nervous System (2016, neutral): “…the subventricular zone (SVZ) appears above the VZ and enlarges dramatically over the course of early and mid-fetal development (Bystron et al., 2008; Dehay et al., 2015; Fietz et al., 2010, 2012; Florio et al., 2015; Hansen et al., 2010; Johnson et al., 2015; Meyer, 2007; Smart et al., 2002).”
Microglia regulate the number of neural precursor cells in the developing cerebral cortex (2013, background): “…that translocate out of the VZ (Schmechel and Rakic, 1979; Voigt, 1989; deAzevedo et al., 2003; Noctor et al., 2004; Noctor et al., 2008) and express Pax6 (Fietz et al., 2010; Hansen et al., 2010; Martínez-Cerdeño et al., 2012) contribute to a reduction in the size of the VZ precursor cell pool.”