Self-organization of axial polarity, inside-out layer pattern, and species-specific progenitor dynamics in human ES cell–derived neocortex

By Taisuke Kadoshima, Hideya Sakaguchi, Tokushige Nakano, Mika Soen, S. Ando, Mototsugu Eiraku, Y. Sasai. Proceedings of the National Academy of Sciences of the United States of America, 2013

914 citations recorded by the source corpus.

Subfields: Biomedical Engineering, Cellular and Molecular Neuroscience, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/8b2a608a65d2298fcc4e145917d0edd6f6bfc00b

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Citations in the corpus

Organogenesis in a dish: Modeling development and disease using organoid technologies (2014, methodology): “This method has further been improved in a recent study (55) that also showed neuronal layering reminiscent of early cerebral cortical development.”
Brain Region-specific Organoids using Mini-bioreactors for Modeling ZIKV Exposure (2016, neutral): “This and other human cerebral organoid technologies (Kadoshima et al., 2013; Lancaster et al., 2013; Cell.”
Stem Cell Organoid Engineering (2016, neutral): “…(serumfree floating culture of embryoid body-like aggregates with quick re-aggregation) protocol has been used to generate the more complex architectures, such as sub-brain regions like the cerebral cortex (Danjo et al., 2011; Eiraku et al., 2008; Kadoshima et al., 2013; Mariani et Cell Stem Cell.”
Brain organoids: advances, applications and challenges (2019, methodology): “As this neuronal layer expands in size and becomes more condensed, it exhibits a compact morphology and starts to resemble the CP of the fetal cortex, with the help of ECM proteins supplemented in culture medium to reconstitute the basement membrane on the organoid surface (Kadoshima et al., 2013; L”