OSVZ progenitors of human and ferret neocortex are epithelial-like and expand by integrin signaling

By S. Fietz, I. Kelava, J. Vogt, Michaela Wilsch‐Bräuninger, D. Stenzel, J. Fish, D. Corbeil, Axel Riehn, W. Distler, Robert Nitsch and 1 more. Nature Neuroscience, 2010

782 citations recorded by the source corpus.

Subfields: Cancer Research, Developmental Neuroscience, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/eab16205bee89f2b6b981e46fab28d778ea3f08a

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Citations in the corpus

A role for intermediate radial glia in the tangential expansion of the mammalian cerebral cortex. (2011, methodology): “A recent report proposed that the ferret SVZ contains 2 classes of progenitors: type ISVZ and type OSVZ (Fietz et al. 2010).”
The cell biology of neurogenesis: toward an understanding of the development and evolution of the neocortex. (2014, background): “The basal endfoot is also thought to convey signals from the extracellular matrix–rich basal lamina, maintaining the proliferative capacity of cortical stem and progenitor cells (Fietz et al. 2010).”
Neural progenitors, neurogenesis and the evolution of the neocortex (2014, background): “Triggered by the previous observations that interfering with integrin αvβ3 signaling reduces the bRG pool size in ferret (Fietz et al., 2010) and that expression of this integrin is sustained in the human oSVZ as compared with human VZ but is reduced in the mouse SVZ as compared with mouse VZ…”
Microglia regulate the number of neural precursor cells in the developing cerebral cortex (2013, background): “…that translocate out of the VZ (Schmechel and Rakic, 1979; Voigt, 1989; deAzevedo et al., 2003; Noctor et al., 2004; Noctor et al., 2008) and express Pax6 (Fietz et al., 2010; Hansen et al., 2010; Martínez-Cerdeño et al., 2012) contribute to a reduction in the size of the VZ precursor cell pool.”
Human adult neurogenesis: evidence and remaining questions (2018, neutral): “…is an example of where, in the human brain, a common developmental principle has evolved to greater complexity: a precursor cell population that is only transient in mice and rats became the foundation of the massive expansion and gyrification of the neocortex in primates (Fietz et al., 2010).”
Development and Evolution of the Human Neocortex (2011, positive): “Increases in neocortical volume and surface area, particularly in the human, are related to the expansion of progenitor cells in the outer subventricular zone (OSVZ) during development (Smart et al., 2002; Hansen et al., 2010; Fietz et al., 2010).”
Human cerebral cortex development from pluripotent stem cells to functional excitatory synapses (2012, background): “Although neuroepithelial ventricular zone cells are the primary stem and progenitor population of the cerebral cortex, at least two secondary progenitor cell populations, basal progenitor cells and outer radial glial cells (oRG), have been identified in mouse, ferret and human”
Molecular Identity of Human Outer Radial Glia During Cortical Development (2015, positive): “Thus, vRG and oRG cells reside in distinct niches defined by differences in anatomical location, provision of growth factors, cell morphology, and behavior (Fietz et al., 2010).”