Self-assembling peptide hydrogel fosters chondrocyte extracellular matrix production and cell division: Implications for cartilage tissue repair

By J. Kisiday, Moonsoo M. Jin, B. Kurz, H. Hung, C. Semino, Shuguang Zhang, Alan J. Grodzinsky. Proceedings of the National Academy of Sciences of the United States of America, 2002

1,036 citations recorded by the source corpus.

Subfields: Biomaterials, Cell Biology

View Paper: https://www.semanticscholar.org/paper/b46ce2fae0fd4c5279e9cedde085671e5e20b2c2

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Citations in the corpus

Cell Encapsulation in Biodegradable Hydrogels for Tissue Engineering Applications (2008, neutral): “However, one of the drawbacks of self-assembled peptides is their weak mechanical properties.(74)”
Nanofibers and their applications in tissue engineering (2006, neutral): “More recently, nanofiberbased scaffolding systems are being explored as scaffolds for tissue engineering (Ma and Zhang 1999; Kisiday et al 2002; Li et al 2002).”
Engineering cartilage tissue. (2008, background): “Kisiday et al showed that articular chondrocytes maintain their phenotype and produce cartilage-like ECM after 4 weeks when encapsulated in self-assembling peptide KLD-12 hydrogels in vitro [148] and respond to dynamic compression loading, with an increase in proteoglycan synthesis and mechanical pr”
Designer Self-Assembling Peptide Nanofiber Scaffolds for Adult Mouse Neural Stem Cell 3-Dimensional Cultures (2006, methodology): “Although we here only used mouse neural stem cells to carry out this study of these designer scaffolds, many cell types have been studied using the pure RADA16 peptide scaffold [12–19] and more are under the way.”
Three-Dimensional Cell Culture Matrices: State of the Art (2008, background): “, proteoglycans and glycosaminoglycans) synthesized from differentiated chondrocytes can be performed without concern about initial contamination of those molecules in the matrix.(111) Synthetic hydrogels normally are not explicitly bioactive, and harsh polymerization conditions (i.”