Cell Encapsulation in Biodegradable Hydrogels for Tissue Engineering Applications

By G. Nicodemus, S. Bryant. Tissue engineering. Part B, Reviews, 2008

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Alginate-Based Biomaterials for Regenerative Medicine Applications (2013, background): “When cells are incorporated into hydrogels, their highly swollen state facilitates transport of nutrients into and cellular waste out of the hydrogels [19–25].”
Collagen for bone tissue regeneration. (2012, background): “, electrospinning [67–74]”
Additive manufacturing of tissues and organs (2012, background): “However, degradation sites can be incorporated into hydrogels, allowing for cell-mediated matrix degradation permitting migration and proliferation [95–97].”
Hydrogels for Biomedical Applications: Their Characteristics and the Mechanisms behind Them (2017, background): “Hydrogels, with high water content as well as tissue-like mechanical properties, have been demonstrated to be capable of combining with cells to engineer various tissues in both vitro and vivo [69,70].”
Three-Dimensional Scaffolds for Tissue Engineering Applications: Role of Porosity and Pore Size (2013, neutral): “82,83 86 Currently, the main limitation of cell encapsulation is the balance between appropriate diffusion coefﬁcient for the transport of oxygen and nutrients to the cells and to the retention of immunoprotective properties.”