Bcl-2-family proteins and the role of mitochondria in apoptosis.
By T. Kuwana, D. Newmeyer. Current Opinion in Cell Biology, 2003
668 citations recorded by the source corpus.
Subfields: Epidemiology, Molecular Biology
View Paper: https://www.semanticscholar.org/paper/52693d9c9878e3ca815f124e1dd546ea8c042eaf
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Epidemiology
- Christine Robson
- G. C. Vanlerberghe
- Sasan Amirsadeghi
- Douglas R. Green
- O. Maier
- Roman Fischer
- Guido Kroemer
- Beth Levine
In Molecular Biology
- Douglas R. Green
- J. Chipuk
- L. Bouchier-Hayes
- G. C. Vanlerberghe
- Christine Robson
- Sasan Amirsadeghi
- O. Maier
- Roman Fischer
Citations in the corpus
- BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly. (2005, background): “Thus, they could not show definitively that BH3 ptosis (Gross et al., 1999; Kuwana and Newmeyer, 2003; domains could act directly to activate Bax rather than Vander Heiden and Thompson, 1999).”
- Interrelation of Oxidative Stress and Inflammation in Neurodegenerative Disease: Role of TNF (2015, background): “The removal of dysfunctional mitochondria by autophagy is especially important, since mitochondrial damage can initiate apoptosis by release of cytochrome C and proapoptotic factors such as SMAC/Diablo [35, 41].”
- Molecular Mechanisms of Ischemia-Reperfusion Injury in Brain: Pivotal Role of the Mitochondrial Membrane Potential in Reactive Oxygen Species Generation (2012, neutral): “, AIF, Smac/Diablo) [121, 122].”
- The role of the mitochondrion in plant responses to biotic stress (2007, positive): “In part, this hypothesis derives from studies of animal apoptosis, where mitochondria play an active role (see reviews by Bratton and Cohen 2001, Crompton 1999, Kuwana and Newmeyer 2003, Ly et al. 2003, Newmeyer and Ferguson-Miller 2003, van Loo et al. 2002).”
- Mitochondrial outer membrane permeabilization during apoptosis: the innocent bystander scenario (2006, background): “Members of the BCL-2 protein family are distinguished by the presence of up to four different BCL-2 homology domains (designated BH1–4).(6) Generally speaking, those that contain”