Chemical and molecular mechanisms of antioxidants: experimental approaches and model systems

By Jianming Lü, P. Lin, Q. Yao, Changyi J. Chen. Journal of Cellular and Molecular Medicine, 2009

1,222 citations recorded by the source corpus.

•  Introduction •  Free radical scavenging ‐  Scavenging superoxide and other ROS ‐  Scavenging hydroxyl radical and other ROS ‐  Stable radical scavenging •  Metal ion (Fe2+, Fe3+, Cu2+ and Cu+) chelating •  Inhibition of free radical generating enzymes •  Activation of internal antioxidant enzymes •  Prevention of lipid peroxidation •  Prevention of DNA damage •  Prevention of protein modification •  Conclusions

Subfields: Biochemistry, Organic Chemistry

View Paper: https://www.semanticscholar.org/paper/f2855fc8a92237759353db49d5430474d4c6f0bb

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Citations in the corpus

• Oxidative Stress and Lipid Peroxidation Products in Cancer Progression and Therapy (2012, background): “ROS are generated as by-products of cellular metabolism, primarily in the mitochondria [3] and include free radicals such as superoxide anion (O2 −•), perhydroxyl radical (HO2•), hydroxyl radical (•OH), nitric oxide (NO), and other species such as hydrogen peroxide (H2O2), singlet oxygen ((1)O2), hy”