NIH Molecular Libraries Initiative
By C. Austin, L. Brady, Thomas R. Insel, F. S. Collins. Science, 2004
316 citations recorded by the source corpus.
Subfields: Computational Theory and Mathematics, Molecular Biology, Public Health, Environmental and Occupational Health
View Paper: https://www.semanticscholar.org/paper/b0a6f5e8b031437b9b4a03a585b372d70e025513
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Computational Theory and Mathematics
- Stephen H. Bryant
- Evan E. Bolton
- Sunghwan Kim
- Paul A. Thiessen
- Jiyao Wang
- Jian Zhang
- Siqian He
- Benjamin A. Shoemaker
In Molecular Biology
- Stephen H. Bryant
- Benjamin A. Shoemaker
- Siqian He
- Jian Zhang
- Paul A. Thiessen
- Yanli Wang
- Tiejun Cheng
- Jiyao Wang
Citations in the corpus
- PubChem BioAssay: 2017 update (2016, methodology): “High-throughput screening (HTS) data were provided by laboratories and screening centers from academic institutes, universities, government organizations as well as pharmaceu-* D956 Nucleic Acids Research, 2017, Vol. 45, Database issue (8,9).”
- The Toxicity Data Landscape for Environmental Chemicals (2008, methodology): “The organizing principles for the design of the chemical/assay system are largely derived from the PubChem project, which captures chemical structure and HTS information on millions of chemicals in its role as the main data repository for the NIH Molecular Libraries Roadmap (Austin et al. 2004).”
- ChemMine. A Compound Mining Database for Chemical Genomics1 (2005, background): “It complements existing molecular and genetics tools (e.g. mutagenesis, RNAi) by allowing fine-tunable in vivo modulations of protein functions and cellular processes (Blackwell and Zhao, 2003; Austin et al., 2004; Lipinski and Hopkins, 2004).”
- PubChem as a public resource for drug discovery (2010, background): “The characteristics of small molecules make them not only as drugs that modulate physiological functions, but also as chemical tools that interrogate the functions of novel genes, pathways and cells [3].”
- The ToxCast program for prioritizing toxicity testing of environmental chemicals. (2007, methodology): “The NCGC is using industrial-scale HTS technologies to collect data that is useful for developing small-molecule chemical probes for basic biological research (Austin et al., 2004).”