Preferential incorporation of adult-generated granule cells into spatial memory networks in the dentate gyrus

By N. Kee, C. Teixeira, Afra H. Wang, Paul W. Frankland. 2007

915 citations recorded by the source corpus.

Subfields: Cognitive Neuroscience, Developmental Neuroscience, Neurology

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Citations in the corpus

Adult Neurogenesis in the Mammalian Brain: Significant Answers and Significant Questions (2011, background): “First, adult-born neurons are preferentially activated by specific inputs as indicated by immediate early gene expression in both hippocampus (Kee et al., 2007; Ramirez-Amaya et al., 2006) and olfactory bulb (Belnoue et al.”
New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory? (2010, background): “For example, MWM learning by a mouse when a set of adult-born DGCs was at least 4–6 weeks of age led to preferential activation of these cells during memory retrieval in the MWM when the DGCs were 10 weeks ol”
Seizure-Associated, Aberrant Neurogenesis in Adult Rats Characterized with Retrovirus-Mediated Cell Labeling (2007, methodology): “Detecting c-fos in newborn neurons after synaptic activation has been used to study the responsiveness of newborn neurons in the adult hippocampus (Jessberger and Kempermann, 2003; Kee et al., 2007; Tashiro et al., 2007).”
Maze training in mice induces MRI-detectable brain shape changes specific to the type of learning (2011, background): “…and dendritic spine numbers (Lendvai et al., 2000; Holtmaat et al., 2005; Lippman and Dunaevsky, 2005), axonal and dendritic branch remodelling (De Paola et al., 2006), neurogenesis (Christie and Cameron, 2006; Kee et al., 2007), and astrocyte morphology (Haber et al., 2006; Todd et al., 2006).”
Adult-born hippocampal dentate granule cells undergoing maturation modulate learning and memory in the brain (2009, background): “However, physiological studies have revealed that adult-born DGCs, 4 – 6 weeks of age, also had enhanced plasticity and were preferentially incorporated into memory traces (Ge et al., 2007; Kee et al., 2007).”
RBPJκ-Dependent Signaling Is Essential for Long-Term Maintenance of Neural Stem Cells in the Adult Hippocampus (2010, background): “There is growing evidence that adult hippocampal neurogenesis is important for hippocampus-dependent learning (Kee et al., 2007; Imayoshi et al., 2008; Clelland et al., 2009; Deng et al., 2009; Jessberger et al., 2009) and that impaired neurogenesis may contribute to hippocampal dysfunction observed”
Brain-derived Neurotrophic Factor Promotes Differentiation and Maturation of Adult-born Neurons Through GABAergic Transmission (2012, background): “Two such genes, Arc and Zif268, are induced by activity in newly generated adult-born dentate gyrus neurons (Bruel-Jungerman et al., 2006; Kee et al., 2007).”
Nuclear factor of activated T cells (NFATc4) is required for BDNF-dependent survival of adult-born neurons and spatial memory formation in the hippocampus (2012, background): “Indeed it has been demonstrated that the newborn neurons are incorporated into DG circuits supporting water maze memory (1, 55) and that spatial learning influences the survival of newborn neurons (56).”
Spatial Learning Depends on Both the Addition and Removal of New Hippocampal Neurons (2007, background): “not occur until they were at least 4 wk old [50].”
GABA-CREB signalling regulates maturation and survival of newly generated neurons in the adult hippocampus (2009, background): “Neurons that have survived this period are incorporated for an extended time into the hippocampal network (Dayer et al., 2003; Kempermann et al., 2003; Kee et al., 2007; Tashiro et al., 2007).”
Diabetes impairs hippocampal function through glucocorticoid-mediated effects on new and mature neurons (2008, background): “, newly generated neurons are activated after this task at a higher rate than mature neuron”
Retrograde monosynaptic tracing reveals the temporal evolution of inputs onto new neurons in the adult dentate gyrus and olfactory bulb (2013, background): “Proc Natl Acad Sci USA 107(50):21848–21853.”
Development of neural stem cell in the adult brain. (2008, background): “One hypothesis is that new neurons are preferentially incorporated into special circuitry to support specific brain functions, as suggested by findings based on the expression of immediate early genes such as Arc and c-Fos [42 ,43,44].”
A critical period for enhanced synaptic plasticity in newly generated neurons of the adult brain. (2007, neutral): “One potential mechanism for such biased recruitment is selective survival of overproduced immature neurons at the cell age of around 2 weeks in response to experience (Kee et al., 2007; Tashiro et al., 2006, 2007).”
Dentate gyrus-specific knockdown of adult neurogenesis impairs spatial and object recognition memory in adult rats. (2009, background): “become preferentially integrated into networks coding for spatial memory (Kee et al. 2007).”
Adult neurogenesis modulates the hippocampus-dependent period of associative fear memory. (2009, background): “the formation of new memory (Dupret et al., 2008; Imayoshi et al., 2008; Kee et al., 2007; Saxe et al., 2006; Shors et al., 2001; Winocur et al., 2006; Zhang et al., 2008; Zhao et al., 2008), and the decay process of HPC dependency of memory over time (this study).”