Functional expression of indoleamine 2,3-dioxygenase by murine CD8α+ dendritic cells

By Francesca Fallarino, C. Vacca, C. Orabona, M. L. Belladonna, R. Bianchi, B. Marshall, D. Keskin, A. Mellor, M. Fioretti, U. Grohmann and 1 more. 2002

251 citations recorded by the source corpus.

Subfields: Behavioral Neuroscience, Biological Psychiatry, Neurology

View Paper: https://www.semanticscholar.org/paper/af3244ae76c4eadaca8a6755b16f943ca99026de

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Behavioral Neuroscience

1. D. Munn
2. A. Mellor

In Biological Psychiatry

1. D. Munn
2. A. Mellor
3. W. Zou

Citations in the corpus

• T cell apoptosis by tryptophan catabolism (2002, background): “More recently, macrophages and DC were found to differ significantly in their patterns of IDO expression, with CD8 DC being highly effective in mediating IDO-dependent apoptosis of T cells in vitro.(7) While inhibition of T cell proliferation by tryptophan depletion likely represents a critical comp”
• Ido expression by dendritic cells: tolerance and tryptophan catabolism (2004, result): “fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=925">CD8α + DCs were found to catabolize tryptophan when exposed to IFN-γ, whereas other (CD8α − ) DCs did not, even though both subsets expressed comparable amounts of IDO protein as analysed by western blo”