Extensive modulation of a set of microRNAs in primary glioblastoma.

By S. Ciafrè, Silvia Galardi, A. Mangiola, M. Ferracin, C. G. Liu, G. Sabatino, M. Negrini, G. Maira, Carlo Maria Croce, M. Farace. Biochemical and Biophysical Research Communications - BBRC, 2005

1,168 citations recorded by the source corpus.

Subfields: Cancer Research, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/ab427c11af1ca925597b823b05122e62661843b5

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Citations in the corpus

miR-21: a small multi-faceted RNA (2008, result): “Elevated expression of miR-21 in GBM was further confirmed by an independent study [2].”
Modulation of K-ras-dependent lung tumorigenesis by microRNA-21 (2010, positive): “Further miRNA profiling in tumor samples and cancer cell lines showed increased miR-21 expression in glioblastoma (Chan et al., 2005; Ciafre et al., 2005), head and neck carcinomas (Tran et al.”
MicroRNA-cancer connection: the beginning of a new tale. (2006, background): “Cancer-specific miRNA fingerprints were identified in every type of analyzed cancer, including B-CLL (10), breast carcinoma (11), primary glioblastoma (12), hepatocellular carcinoma (13), papillary thyroid carcinoma (14), lung cancer (15–17), gastric carcinoma, colon carcinoma (18), and endocrine pa”
Regulation of the p27Kip1 tumor suppressor by miR‐221 and miR‐222 promotes cancer cell proliferation (2007, background): “It was recently shown that high level of miR-221&222 is part of a signature for poor prognosis in glioblastomas (Ciafre et al, 2005).”
MicroRNA miR-21 overexpression in human breast cancer is associated with advanced clinical stage, lymph node metastasis and patient poor prognosis. (2008, background): “Aberrant expression of miRNAs has been linked to some cancers (Caldas and Brenton 2005; Croce and Calin 2005), leading to the use of miRNA profiles in the diagnosis/prognosis of specific cancers and to distinguish certain cancer types (Calin et al. 2004, 2005; Takamizawa et al. 2004; Eis et al.…”
MicroRNA (miRNA) in cancer (2015, neutral): “[21,22,65-68].”
The Expression of MicroRNA miR-107 Decreases Early in Alzheimer's Disease and May Accelerate Disease Progression through Regulation of β-Site Amyloid Precursor Protein-Cleaving Enzyme 1 (2008, background): “DOI:10.1523/JNEUROSCI.5065-07.2008 Copyright © 2008 Society for Neuroscience 0270-6474/08/281213-11$15.00/0 which miRNAs are expressed during various normal and abnormal brain states, including in brain diseases (Babak et al., 2004; Ciafre et al., 2005; Nelson et al., 2006; Perkins et al., 2007).”
microRNA-7 inhibits the epidermal growth factor receptor and the Akt pathway and is down-regulated in glioblastoma. (2008, background): “It shouldalso be noted that although we do not show that the defect in glioblastoma microRNA processing is selective andnot global, this is ind icated by reports showing pronouncedoverexpression of some microRNAs in glioblastoma versus normal brain ( 4 , 19).”
Targeting of the Bmi-1 oncogene/stem cell renewal factor by microRNA-128 inhibits glioma proliferation and self-renewal. (2008, background): “miR profiling has revealed distinct expression signatures in various human cancers, including glioma ( 9 ).”
microRNAs as oncogenes and tumor suppressors. (2007, background): “These are highly invasive, very aggressive, and one of the most incurable cancers in humans (Ciafre et al., 2005).”