Glial regulation of the cerebral microvasculature

By C. Iadecola, Maiken Nedergaard. Nature Neuroscience, 2007

1,131 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Neurology

View Paper: https://www.semanticscholar.org/paper/aa14befca1de33638eebd2f272f7d3ebc2d7a38b

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cellular and Molecular Neuroscience

1. M. Sofroniew
2. M. Pekny
3. Igor Allaman
4. M. Pekna
5. Pierre J. Magistretti
6. Maiken Nedergaard
7. Y. Ao
8. B. Song

In Neurology

1. M. Sofroniew
2. M. Pekny
3. M. Pekna
4. Igor Allaman
5. Pierre J. Magistretti
6. Maiken Nedergaard
7. Y. Ao
8. Praveen Ballabh

Citations in the corpus

• Integrative regulation of human brain blood flow (2014, background): “Numerous excellent reviews have been written on the topic which, being beyond the purview of this review, will not be detailed here (Iadecola, 2004; Girouard & Iadecola, 2006; Hamel, 2006; Iadecola & Nedergaard, 2007; Jakovcevic & Harder, 2007).”
• Dynamic causal modelling: A critical review of the biophysical and statistical foundations (2011, background): “Also, DCM for fMRI has also ignored the important role of glial cells (Takano et al., 2006; Iadecola and Nedergaard, 2007).”
• The blood-brain barrier: an engineering perspective (2013, background): “Astrocytes form contacts with microvessels and the synapses between neurons, and play an important role in matching oxygen and glucose transport to neural activity through regulation of local blood flow (Zonta et al., 2003; Iadecola, 2004; Takano et al., 2006; Iadecola and Nedergaard, 2007).”
• Blood–brain barrier structure and function and the challenges for CNS drug delivery (2013, background): “Recent studies show that a complex local grouping of non-neuronal cells supports groups of neurons within a modular neurovascular unit, initially described in relation to regulation of local cerebral blood flow at the level of cerebral arterioles, and involving astrocytes and smooth muscle cells (Ia”
• Glia and pain: Is chronic pain a gliopathy? (2013, background): “Central sensitization and LTP are also involved in human pain conditions [134,285].”
• Astrocytes: biology and pathology (2009, neutral): “coordinated manner [86, 102].”
• Regional blood flow in the normal and ischemic brain is controlled by arteriolar smooth muscle cell contractility and not by capillary pericytes (2015, neutral): “…tree, especially at the transition between arterioles and terminal capillaries, are the primary sites of CBF regulation remains a topic of debate (Armulik et al., 2011; Hamilton et al., 2010; Iadecola and Nedergaard , 2007; Itoh and Suzuki, 2012; Krueger and Bechmann, 2010; Winkler et al., 2011).”
• The perivascular astroglial sheath provides a complete covering of the brain microvessels: An electron microscopic 3D reconstruction (2010, background): “…sheath and intercellular Ca21 signaling Another implication of our finding of a complete and overlapping endfoot coverage is that the endfeet may provide a continuous avenue for signaling along the brain microvessels (Iadecola and Nedergaard, 2007; Nedergaard et al., 2003; Scemes and Giaume, 2006).”
• STAT3 is a critical regulator of astrogliosis and scar formation after spinal cord injury (2008, background): “Signaling regulation of astrocyte roles after SCI Astrocytes exert many activities essential to normal CNS function (Kettenmann and Ransom, 2004; Christopherson et al., 2005; Gensert and Ratan, 2006; Iadecola and Nedergaard, 2007; Pellerin et al., 2007).”
• Diffusion MRI at 25: Exploring brain tissue structure and function (2012, background): “coupling are not yet fully understood (Iadecola and Nedergaard, 2007; Magistretti and Pellerin, 1999) and the BOLD signal depends”