Immune surveillance of tumors.
By J. Swann, M. Smyth. Journal of Clinical Investigation, 2007
1,432 citations recorded by the source corpus.
Subfields: Immunology, Oncology
View Paper: https://www.semanticscholar.org/paper/aa0b52cd8fffda100a033b0422e1209266c50ffd
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Immunology
- A. Anderson
- V. Kuchroo
- A. Labani-Motlagh
- A. Steinle
- B. Blazar
- Mehrnoush Ashja-Mahdavi
- Richard J. Simpson
- George Coukos
In Oncology
Citations in the corpus
- Tumor-Derived Lactate Modifies Antitumor Immune Response: Effect on Myeloid-Derived Suppressor Cells and NK Cells (2013, background): “T here is increasing evidence that a defect in immune surveillance results in tumor growth (1, 2).”
- The Tumor Microenvironment: A Milieu Hindering and Obstructing Antitumor Immune Responses (2020, background): “Cancer-associated fibroblasts (CAFs) are derived from different origins: (1) TGF-β-activated resident fibroblasts; (2) EMT; (3) EndMT; (4) smooth muscle actinupregulated stellate cells; (5) CAAs; or (6) mesenchymal stem cells with TGF-β overexpression or via CXCL16-CXCR6 (150).”
- Immune evasion in cancer: Mechanistic basis and therapeutic strategies. (2015, neutral): “Thus, a balance between immune control and tumor growth is maintained, giving the appear ance 146 of tumor dormancy [15].”
- Modulation of the anti-tumor immune response by complement (2008, background): “1655" language="eng" relation="no"> The diverse functions of the immune system in cancer initiation and development are illustrated by two ideas: the 'cancer immunoediting' theory, which postulates that the immune system protects the host against cancer developmen”
- Immunity, Inflammation, and Cancer (2010, neutral): “Similar to TAMs, the tumorpromoting functions of T lymphocytes are mediated by cytokines, whereas both cytokines and cytotoxic mechanisms mediate the anti-tumorigenic functions of T lymphocytes (Lin and Karin, 2007; Swann and Smyth, 2007).”
- Exosomes and their roles in immune regulation and cancer. (2015, background): “The immune system embodies ordered biological processes and tructures that serve to recognise and respond to the surrounding immune surveillance [1].”
- Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity (2010, background): “In support of cancer immunosurveillance is the fact that both immunodeficient or immunosuppressed patients and experimental animals are more susceptible to tumor development (for reviews see Dunn et al., 2004; Zitvogel et al., 2006; Swann and Smyth, 2007).”
- NRF2, a Transcription Factor for Stress Response and Beyond (2020, background): “Cancers arise through cancer immunoediting to eventually escape the immune system [136].”
- NK cells and cancer immunosurveillance (2008, background): “Interestingly, mice deficient for both RAG2 and STAT1 have been reported to spontaneously develop adenocarcinoma at higher rates as compared with mice deficient only for RAG2, implicating NK cells in tumour immunosurveillance (Shankaran et al., 2001; Dunn et al., 2004; Swann and Smyth, 2007).”