Tumor-Derived Lactate Modifies Antitumor Immune Response: Effect on Myeloid-Derived Suppressor Cells and NK Cells

By Z. Husain, Yannu Huang, P. Seth, V. Sukhatme. Journal of Immunology, 2013

744 citations recorded by the source corpus.

Subfields: Cancer Research, Immunology

View Paper: https://www.semanticscholar.org/paper/45a7fce5eead095bdf9cb423287f4049f9f637be

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cancer Research

1. J. Pouysségur
2. J. Rathmell

In Immunology

1. M. Mack
2. C. Bogdan
3. C. Blank
4. J. Rathmell

Citations in the corpus

• Targeting Metabolism to Improve the Tumor Microenvironment for Cancer Immunotherapy. (2020, background): “This subsequently resulted in smaller tumors, decreased MDSC frequency, and an overall improved anti-tumor immune response (Husain et al., 2013).”
• LDHA-Associated Lactic Acid Production Blunts Tumor Immunosurveillance by T and NK Cells. (2016, background): “, 2008) and increases the number of MDSCs in the spleens of mice carrying LDHA-expressing tumors (Husain et al., 2013).”