Liver Organogenesis Promoted by Endothelial Cells Prior to Vascular Function

By Kunio Matsumoto, H. Yoshitomi, Janet Rossant, K. Zaret. Science, 2001

876 citations recorded by the source corpus.

Subfields: Cancer Research, Hepatology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/a8b18af921d75e417a149943c350026968fd4d34

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cancer Research

1. K. Walsh
2. I. Shiojima
3. G. Genové
4. C. Betsholtz
5. A. Armulik
6. S. Levenberg
7. J. Rouwkema
8. Berislav Zlokovic

In Molecular Biology

1. A. Armulik
2. G. Genové
3. S. Levenberg
4. K. Walsh
5. I. Shiojima
6. C. Betsholtz
7. J. Rouwkema
8. Berislav Zlokovic

Citations in the corpus

• Pericytes: developmental, physiological, and pathological perspectives, problems, and promises. (2011, background): “…in cancer, is proposed by many studies but is still largely unclear (indicated by ‘‘?’’). development, the developing vasculature has been shown to have a role in tissue induction that goes beyond the simple supply of nutrients and oxygen (Lammert et al., 2001; Matsumoto et al., 2001).”
• Disruption of coordinated cardiac hypertrophy and angiogenesis contributes to the transition to heart failure. (2005, positive): “For example, it has been shown that normal development of liver or pancreas requires unknown paracrine factor(s) released from endothelial cells (46, 47) and hepatocyte growth factor secreted from liver endothelial cells promotes hepatocyte proliferation (48).”
• Engineering vascularized skeletal muscle tissue (2005, background): “Cocultures with endothelial cells may also be important for inducing differentiation of engineered tissues, as embryonic endothelial cells are critical for the earliest stages of organogenesi”
• Organogenesis of lymphoid tissues (2003, background): “It is of interest that for pancreas and liver organogenesis, the earliest signals were shown to be derived from vasculogenic endothelial cell”
• The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors (2002, background): “with those reported here, we propose that Pdx1 expression marks a territory of endoderm with intrinsic foregut competence, with this region becoming further subdivided by specific intercellular signaling events driving cells towards liver or pancreas specificatio”