Pre-B cell colony-enhancing factor inhibits neutrophil apoptosis in experimental inflammation and clinical sepsis.

By S. Jia, Yue Li, J. Parodo, A. Kapus, Lingzhi Fan, O. Rotstein, J. Marshall. Journal of Clinical Investigation, 2004

634 citations recorded by the source corpus.

Subfields: Epidemiology, Immunology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/a867d617693f0abd64bfae134b192776e62a8fdb

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Epidemiology

1. Herbert Tilg
2. A. Moschen
3. J. Bastard
4. A. Kaser
5. B. Fève
6. S. Imai

In Immunology

1. R. Busse

In Molecular Biology

1. A. Kaser
2. R. Busse
3. S. Imai
4. Herbert Tilg
5. A. Moschen
6. K. Mills
7. L. Guarente
8. G. Steinberg

Citations in the corpus

• Adipokines as emerging mediators of immune response and inflammation (2007, background): “Visfatin Visfatin is an insulin-mimetic adipokine that was originally discovered in liver, skeletal muscle and bone marrow as a growth factor for B lymphocyte precursors (whence its alternative name, pre-B-colony enhancing factor, or PBEF)”
• Elevated plasma level of visfatin/pre-B cell colony-enhancing factor in patients with type 2 diabetes mellitus. (2006, background): “cytes, and neutrophils (11); stimulates the expression of IL-6”
• Adipokines: the missing link between insulin resistance and obesity. (2008, background): “[86] Jia SH, Li Y, Parodo J, Kapus A, Fan L, Rotstein OD, et al.”
• Visfatin, an Adipocytokine with Proinflammatory and Immunomodulating Properties1 (2007, background): “Because PI3K is critically involved in the control of cell death by activating the survival kinase Akt (30), induction of PI3K could be a possible mechanism involved in visfatin’s antiapoptotic properties as reported in previously published data (31, 32).”
• Nampt/PBEF/Visfatin regulates insulin secretion in beta cells as a systemic NAD biosynthetic enzyme. (2007, background): “Additionally, because this protein lacks a signal sequence for secretion, it has been suggested that the presence of Nampt/PBEF/visfatin in extracellular compartments might be simply due to either cell lysis or cell death (Hug and Lodish, 2005; Stephens and Vidal-Puig, 2006).”
• Macrophages in human visceral adipose tissue: increased accumulation in obesity and a source of resistin and visfatin (2006, background): “Moreover, visfatin is also considered to be an inflammatory cytokine (pre-B cell colony-enhancing factor) in neutrophils [13].”
• Adipocytokines: mediators linking adipose tissue, inflammation and immunity (2006, background): “Furthermore, expression of visfatin has been shown to be upregulated in activated neutrophils and to inhibit the apoptosis of neutrophil”