Nuclear Localization of NPR1 Is Required for Activation of PR Gene Expression

By M. Kinkema, Weihua Fan, Xinnian Dong. The Plant Cell, 2000

713 citations recorded by the source corpus.

Subfields: Molecular Biology, Plant Science

View Paper: https://www.semanticscholar.org/paper/70223e26e2bbd25712881e20f54e175edbe3690c

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Citations in the corpus

The Arabidopsis NPR1 protein is a receptor for the plant defense hormone salicylic acid. (2012, background): “, 2000) and nuclear localization is critical to activate PR-1 (Kinkema et al., 2000).”
Contrasting mechanisms of defense against biotrophic and necrotrophic pathogens. (2005, background): “The monomers then enter the nucleus, where they interact with TGA-type transcription factors (28, 29, 41, 61, 65, 85, 129).”
A Genomic Approach to Identify Regulatory Nodes in the Transcriptional Network of Systemic Acquired Resistance in Plants (2006, background): “SA induces nuclear translocation of the transcription cofactor NPR1 to activate many genes required for disease resistance [1].”
Jasmonate‐regulated Arabidopsis stress signalling network (2005, background): “PR genes (Kinkema et al. 2000), interaction between SA and JA is modulated through NPR1 in the cytosol (Spoel et al.”
The salicylic acid loop in plant defense. (2003, background): “Application of SA or its analogs stimulates the translocation of NPR1 into the nucleus [28], which is required for the activation of downstream signaling.”
Recognition and response in the plant immune system. (2003, background): “Although NPR1 protein is transported into the nucleus in response to SAR induction, and its nuclear localization is required for SAR-induced PRgene activation (78), NPR1 itself probably does not act as a transcription factor.”
Plant growth-promoting rhizobacteria (PGPR): Their potential as antagonists and biocontrol agents (2012, background): “These monomers are translocated to the nucleus (Kinkema et al. 2000), where they interact with members of the TGA/OBF subclass of basic-leucine-zipper (bZIP) transcription factors that are involved in SA-dependent activation of PR genes (Fan and Dong, 2002; Zhang et al.”
Systemic acquired resistance: turning local infection into global defense. (2013, neutral): “The SA-induced oligomer-to-monomer switch of NPR1 is a critical step in inducing SAR, as the NPR1 monomer is nuclear translocated and required for resistance (69, 95).”
Inducers of plant systemic acquired resistance regulate NPR1 function through redox changes. (2003, background): “NPR1 gene is constitutive, influenced only moder- npr1-1 mutant background (Kinkema et al., 2000).”
Evidence for an Important Role of WRKY DNA Binding Proteins in the Regulation of NPR1 Gene Expression (2001, background): “SNI1 may be a negative regulator of SAR that is inactivated by NPR1 after SA treatment or pathogen infection (Li et al., 1999).”