DEMETER, a DNA glycosylase domain protein, is required for endosperm gene imprinting and seed viability in arabidopsis.

By Yeonhee Choi, Mary Gehring, L. Johnson, M. Hannon, J. Harada, R. Goldberg, Steven E. Jacobsen, R. Fischer. Cell, 2002

776 citations recorded by the source corpus.

Subfields: Genetics, Plant Science

View Paper: https://www.semanticscholar.org/paper/a6f3369cd593d1ec4d97c8eb58b9c5f2ed213f6c

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Citations in the corpus

Epigenetic reprogramming and induced pluripotency (2009, background): “Compelling evidence indicates that DNA demethylation can occur by methylcytosine-specific DNA glycosylases and by the base excision repair machinery in plants (Choi et al., 2002; Gong et al., 2002).”
Active DNA demethylation: many roads lead to Rome (2010, background): “Whereas DME was discovered owing to the loss of expression of the imprinted gene MEDEA in a loss-of-function DME mutan”
Gardening the genome: DNA methylation in Arabidopsis thaliana (2005, background): “Although ROS1 is expressed broadly throughout development, a second glycosylase gene, DEMETER ( DME ), has a very specific expression pattern and function during female gametogenesi”
The AUXIN RESPONSE FACTOR 2 gene of Arabidopsis links auxin signalling, cell division, and the size of seeds and other organs (2005, methodology): “5 kb of the ARF2 5 flanking sequence fused to a nuclear-localized GFP gene (Choi et al., 2002).”
Comprehending crystalline β-carotene accumulation by comparing engineered cell models and the natural carotenoid-rich system of citrus (2011, neutral): “DME is expressed in the central cell of the female gametophyte (Choi et al., 2002) but not in sperm cells (Schoft et al.”
DEMETER DNA glycosylase establishes MEDEA polycomb gene self-imprinting by allele-specific demethylation. (2006, background): “Expression of MEA and FWA in the central cell and early endosperm is dependent on DME (Choi et al., 2002; Kinoshita et al., 2004).”
Active DNA Demethylation Mediated by DNA Glycosylases (2009, neutral): “Compared with the widespread expression of ROS1 in all plant tissues examined (29), DME is preferentially expressed in the central cell and synergids of the female gametophyte (16).”
Epigenetic inheritance during the cell cycle (2009, background): “Whereas in plants DNA glycosylases that are implicated in DNA demethylation have been characterize”
Epigenetic and chromatin-based mechanisms in environmental stress adaptation and stress memory in plants (2017, background): “elegantly show that paternal inheritance is inhibited by the activity of the DNA glycosylase DEMETER (DME) in the male gametes, and that the transmission of the memory through the father is restored in dme mutants [95, 96].”