Biochemistry of oxidative stress.
By Barry Halliwell. Biochemical Society Transactions, 2007
1,920 citations recorded by the source corpus.
Subfields: Molecular Biology, Organic Chemistry
View Paper: https://www.semanticscholar.org/paper/a638fd8bd6d3391ef700d2d6725d74d2a14ee969
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In Molecular Biology
- K. Jomová
- Isabel C. F. R. Ferreira
- C. Pham-Huy
- Lien Ai Pham-Huy
- R. Stocker
- Hua-Dong He
- A. Cuadrado
- D. Gupta
In Organic Chemistry
Citations in the corpus
- Stress-Activated Cap’n’collar Transcription Factors in Aging and Human Disease (2010, background): “Therefore, oxidative stress can be a causative or exacerbating factor in a range of diseases, including respiratory and metabolic disorders, neurodegenerative diseases, and cancer (24, 25).”
- Clinical Relevance of Biomarkers of Oxidative Stress (2015, background): “Oxidative stress, characterized by an imbalance between oxidants and antioxidants in favor of oxidants, leads to disruption of redox signaling and physiological function (157, 158).”
- Oxidative Stress: A Key Modulator in Neurodegenerative Diseases (2019, background): “Halliwell had established that a free radical is a species having one or more unpaired electrons and existing independently on its own [7,8].”
- Screening microalgae as potential sources of antioxidants (2017, background): “Although oxygen is required for aerobic life, it can promote oxidative stress (Halliwell 2007), which is triggered by an inbalance between the production of reactive oxygen species (ROS) and the antioxidant defenses (Halliwell 1994).”
- Free Radicals, Antioxidants in Disease and Health (2008, background): “The major antioxidant enzymes directly involved in the neutralization of ROS and RNS are: superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx) and glutathione reductase (GRx) (6-12).”
- Melatonin as a natural ally against oxidative stress: a physicochemical examination (2011, background): “They also participate in cellular signaling systems [29, 31, 32, 35] and seem to play a role in the regulation of insulin receptor kinase activity [33] and in the apoptosis of defective cells [36, 37].”
- Biochemistry of Reactive Oxygen and Nitrogen Species (2015, background): “In biochemistry, the free radicals are often referred as ROS, because biologically, the most significant free radicals are oxygen-centered [8, 9].”
- Antioxidant Dynamics in the Live Animal and Implications for Ruminant Health and Product (Meat/Milk) Quality: Role of Vitamin E and Selenium (2014, neutral): “The balance between cellular oxidants and antioxidants is critical, with an imbalance leading to oxidative stress (OS) and damage to cellular lipids, proteins andDNA (Halliwell 2007; Lykkesfeldt and Svendsen 2007; Celi 2011a).”
- Oxidative Stress: Harms and Benefits for Human Health (2017, background): “Proteins may as well being damaged by oxidative stress, undergoing to conformational modifications that could determine a loss, or an impairment, of their enzymatic activity [20, 25].”
- Mechanisms of activation of the transcription factor Nrf2 by redox stressors, nutrient cues, and energy status and the pathways through which it attenuates degenerative disease (2015, neutral): “ROS can damage proteins, lipids, and DNA, and when the burden of ROS in the cell exceeds its antioxidant capability a state of oxidative stress is considered to exist [1].”