Childhood maltreatment predicts unfavorable course of illness and treatment outcome in depression: a meta-analysis.

By Valentina Nanni, Rudolf Uher, A. Danese. American Journal of Psychiatry, 2011

1,421 citations recorded by the source corpus.

Subfields: Clinical Psychology, Pediatrics, Perinatology and Child Health

View Paper: https://www.semanticscholar.org/paper/a5d4417ba3f3996a22aff2ecfac42aac83e6fc50

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Clinical Psychology

1. Bruce S. McEwen
2. C. Nemeroff
3. C. D’Arcy
4. M. Li
5. Xiangfei Meng
6. F. Lotrich
7. J. Felger
8. Richard A. Bryant

In Pediatrics, Perinatology and Child Health

1. C. Nemeroff
2. Bruce S. McEwen
3. A. Danese
4. C. D’Arcy
5. M. Li
6. Xiangfei Meng
7. J. Newbury
8. J. Baldwin

Citations in the corpus

• Adverse childhood experiences, allostasis, allostatic load, and age-related disease. (2012, background): “Finally, a meta-analysis of four studies did not find evidence of volumetric changes in the amygdala of children with maltreatment-related PTSD compared to controls [76].”
• Royal Australian and New Zealand College of Psychiatrists clinical practice guidelines for mood disorders (2015, background): “Significant dysfunctional premorbid personality factors (including child abuse history) (Nanni et al., 2012) and psychosocial precipitating factors suggest that antidepressants may be less likely to achieve remission as Australian & New Zealand Journal of Psychiatry, 49(12) monotherapy.”
• Maltreatment in childhood substantially increases the risk of adult depression and anxiety in prospective cohort studies: systematic review, meta-analysis, and proportional attributable fractions (2015, methodology): “…who report being abused as children exhibited more post-traumatic stress symptoms, cognitive distortion, emotional distress (including depression and anxiety disorders), eating disorders, sleep disorders, substance abuse, and avoidance (Briere & Elliott, 1994; Chen et al. 2010; Nanni et al. 2012).”
• Paradise Lost: The Neurobiological and Clinical Consequences of Child Abuse and Neglect. (2016, methodology): “…(Wiersma et al., 2009), features of atypical depression (hypersomnia, interpersonal rejection sensitivity, increased appetite, leaden limb paralysis) (Withers et al., 2013), and most importantly a poor outcome to treatment with psychopharmacology and/or psychotherapy (Nanni et al., 2012).”
• Hair cortisol, stress exposure, and mental health in humans: a systematic review. (2013, result): “For example, it has been shown in treatment of depressive adult patients, that the incidence of early trauma influences treatment effects, as when receiving monotherapy, patients without early trauma responded better to medication, whereas patients with early trauma responded better to psychotherapy”
• Inflammatory Cytokines in Depression: Neurobiological Mechanisms and Therapeutic Implications (2013, background): “In fact, persons exposed to early life stress have been found to be less responsive to antidepressant interventions (Nemeroff et al., 2003, Nanni et al., 2011).”
• Inflammation: depression fans the flames and feasts on the heat. (2015, background): “Indeed, childhoodmaltreatment is aparticularlypotent risk factor for depression in adults, especially when individuals encounter stressful life events (2, 59).”
• Agreement Between Prospective and Retrospective Measures of Childhood Maltreatment (2019, positive): “On the one hand, underreporting may occur because of (1) deficits in encoding the maltreatment experience in early life owing to immature, delayed, or impaired brain development37; (2) deficits in consolidating the maltreatment memory owing to low emotional valence (ie, not experiencing the event as”