Exosomes as new vesicular lipid transporters involved in cell-cell communication and various pathophysiologies.

By M. Record, Kévin Carayon, M. Poirot, S. Silvente-Poirot. Biochimica et Biophysica Acta, 2014

824 citations recorded by the source corpus.

Subfields: Cancer Research, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/06bfd8bc93687ae12146c60ee283e17307a70115

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Citations in the corpus

Shedding light on the cell biology of extracellular vesicles (2018, neutral): “Extracellular vesicles can transport various lipid species including eicosanoids, fatty acids, and cholesterol as well as lipid translocases, thereby contributing to the regulation of bioactive lipid species 167 .”
Molecular definitions of autophagy and related processes (2017, neutral): “Of note, some proteins internalized by multivesicular bodies through The EMBO Journal Molecular definitions of autophagy Lorenzo Galluzzi et al direct membrane invagination can be spared from degradation and released in the extracellular microenvironment within exosomes (Record et al , 2014).”
SORTING IT OUT: REGULATION OF EXOSOME LOADING (2014, background): “The movement of MVBs along microtubules is in part controlled by the cholesterol content of the cells [55].”
Exosome: A Review of Its Classification, Isolation Techniques, Storage, Diagnostic and Targeted Therapy Applications (2020, neutral): “In addition to marker proteins, specific types of phospholipids present in the lipid bilayer may also be a potential positive control for characterizing the presence of exosomes, 75,76 so it may be considered to develop multiple markers to characterize exosomes in many ways.”
A protocol for exosome isolation and characterization: evaluation of ultracentrifugation, density-gradient separation, and immunoaffinity capture methods. (2015, background): “Despite recent advances in our understanding of exosome biology [13, 17], much of this information has been obtained from heterogeneous or impure exosome preparations, which have confounded interpretation of findings.”
Biological properties of extracellular vesicles and their physiological functions (2015, background): “sphingolipids compared to their parent cells (232).”
Extracellular Vesicles: Unique Intercellular Delivery Vehicles. (2017, background): “Their stability is attributed in part to the lipid content of their membranes, which are enriched in cholesterol, sphingomyelin, annexin, phosphatidylserine and glycosphingolipids, as compared to the cellular plasma membrane [23].”
Lipids in exosomes: Current knowledge and the way forward. (2017, background): “We refer to a recent review covering the possibilities of PS being important for uptake of certain exosomes into target cells [15].”
Current knowledge on exosome biogenesis and release (2017, background): “In addition, these vesicles are suggested to play a role in intercellular communication and have been associated with numerous physiological and pathological functions [2, 11, 12].”