Vital Involvement of a Natural Killer Cell Activation Receptor in Resistance to Viral Infection

By Michael G. Brown, A. Dokun, J. Heusel, H. Smith, D. L. Beckman, Erika A. Blattenberger, Chad Dubbelde, Laurie R. Stone, A. Scalzo, W. Yokoyama. Science, 2001

672 citations recorded by the source corpus.

Subfields: Epidemiology, Immunology

View Paper: https://www.semanticscholar.org/paper/a4667f46560b87888e6853d272a07e86fbf8937a

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Epidemiology

1. R. Khanna
2. B. Beutler
3. T. Crough
4. Shizuo Akira
5. Taro Kawai

In Immunology

1. Shizuo Akira
2. B. Beutler
3. L. Lanier
4. K. Hoebe
5. E. Janssen
6. W. Yokoyama
7. Xin Du
8. A. Cerwenka

Citations in the corpus

• Natural killer cells, viruses and cancer (2001, background): “cgi?l=16639">Ly49H is involved in the resistance to MCMV infectio”
• Inferences, questions and possibilities in Toll-like receptor signalling (2004, background): “; certainly some of the receptors on natural killer cell”
• Identification of Lps2 as a key transducer of MyD88-independent TIR signalling (2003, background): “BALB/c mice, which fail to eliminate the virus as a result of a mutation in the NK-activating receptor LY49”
• Immune functions encoded by the natural killer gene complex (2003, background): “Recently, Cmv1 was shown to encode the NK-cell activating receptor Ly49h in the C57BL/6 mouse strai”
• Immunobiology of Human Cytomegalovirus: from Bench to Bedside (2009, background): “A single autosomal dominant locus, termed Cmv1, contained in the NK gene complex on mouse chromosome 6 controls both survival and viral titers in the murine spleen (226), and this resistance is mediated by the murine NK cell activation receptor Ly-49H, contained in the NK gene complex (34).”