Metagenomic Analysis of the Human Distal Gut Microbiome

By S. Gill, Mihai Pop, R. Deboy, P. Eckburg, Peter J. Turnbaugh, B. Samuel, Jeffrey I. Gordon, David A. Relman, Claire Fraser-Liggett, K. Nelson. Science, 2006

4,540 citations recorded by the source corpus.

Subfields: Molecular Biology, Physiology

View Paper: https://www.semanticscholar.org/paper/a22d9c1518ce5047d4b68097064a5461fdbe8c91

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Citations in the corpus

Characterization of gut microbiomes in nonalcoholic steatohepatitis (NASH) patients: A connection between endogenous alcohol and NASH (2013, background): “First, gut microbiota are known to have a large effect on the digestion and absorption of nutrients.(12) Microbiota transplantation experiments in mice suggested that certain microbiota are capable of inducing obesity independent of other environmental factors.”
WebMGA: a customizable web server for fast metagenomic sequence analysis (2011, background): “It provides revolutionary and unprecedented view of the identities, dynamics and functions of microbial communities in various environments such as marine [1], human gut [2] and many others [3-5].”
A Bioinformatician's Guide to Metagenomics (2008, background): “Other groups published similar but distinct approaches in quick succession (50, 33, 113).”
Scaling laws predict global microbial diversity (2016, background): “Assuming these percentages are reflective of themicrobiome at large and that there are about 10(14)microbial cells in the human gut (5, 28, 46), then Nmax would be in the range from 1.”
Bile Acid Signaling in Metabolic Disease and Drug Therapy (2014, background): “It is suggested that intestinal microbes generate short chain fatty acids from dietary carbohydrates that otherwise cannot be used as energy (Topping and Clifton, 2001; Gill et al., 2006; Turnbaugh et al., 2006).”
The Human Microbiome Project (2007, background): “Together, the genomes of these microbial symbionts (collectively defined as the microbiome) provide traits that humans did not need to evolve on their ow”
Pathological bacterial translocation in liver cirrhosis. (2014, background): “Additionally, only a small proportion of the enteric bacteria can currently be examined by conventional culture techniques [79] limiting diagnostic measures.”
IMG/M: a data management and analysis system for metagenomes (2007, background): “... version of IMG/M (as of September 2007) contains metagenome datasets generated using shotgun sequencing for 10 projects involving a total of 24 microbiome samples, including an acid mine drainage biofilm (5), three isolated deep sea ‘whale fall’ carcass samples, an agricultural soil sample (6), ”
The Role of Microbial Amino Acid Metabolism in Host Metabolism (2015, background): “Furthermore, it has been reported that the microbiota in the large intestine is enriched with genes involved in essential amino acid biosynthesis using precursors derived from the plasma pool in humans [53].”