The Human Microbiome Project
By Peter J. Turnbaugh, Ruth E. Ley, Micah Hamady, Claire Fraser-Liggett, Rob Knight, Jeffrey I. Gordon. Nature, 2007
5,534 citations recorded by the source corpus.
A strategy to understand the microbial components of the human genetic and metabolic landscape and how they contribute to normal physiology and predisposition to disease.
Subfields: Molecular Biology, Physiology
View Paper: https://www.semanticscholar.org/paper/f93cbb26b36c0d0b7190a15bdd13bebcce2e1bdc
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Molecular Biology
- Rob Knight
- Curtis Huttenhower
- Patrick D. Schloss
- Noah Fierer
- Nicola Segata
- C. Lauber
- Ruth E. Ley
- J. Gregory Caporaso
In Physiology
- Rob Knight
- Micah Hamady
- Curtis Huttenhower
- Justin L. Sonnenburg
- E. Sonnenburg
- Peter J. Turnbaugh
- J. Cryan
- Ruth E. Ley
Citations in the corpus
- The Microbiome and Butyrate Regulate Energy Metabolism and Autophagy in the Mammalian Colon (2011, neutral): “These microbiota and their genomes, referred to collectively as the microbiome, are being characterized by metagenomic sequencing as part of the Human Microbiome Project (Gill et al., 2006; Hildebrandt et al., 2009; Kurokawa et al., 2007; Qin et al.; Turnbaugh et al., 2009; Turnbaugh et al., 2007).”
- Inducible Foxp3+ regulatory T-cell development by a commensal bacterium of the intestinal microbiota (2010, background): “B colonize almost every environmentally exposed surface of the human body, with the greatest quantity and diversity found in the lower gastrointestinal tract (1).”
- Integrative analysis of environmental sequences using MEGAN4. (2011, background): “2006), the human body (Turnbaugh et al. 2007), or the digestive tract of humans or animals (Turnbaugh et al.”
- Inference for empirical Wasserstein distances on finite spaces (2016, background): “In particular, the composition of microbial communities in the human gut has been associated with obesity, inflammatory bowel disease and others (Turnbaugh et al., 2007).”
- An expansion of rare lineage intestinal microbes characterizes rheumatoid arthritis (2016, background): “The Human Microbiome Project and other studies have documented the diversity of the gut microbiome in healthy individuals and gut-related diseases [16–19].”
- Metagenomic biomarker discovery and explanation (2011, background): “The human microbiome, consisting of the total microbial complement associated with human hosts, is an important emerging area for metagenomic biomarker discovery [13,14].”
- Intestinal mucosal adherence and translocation of commensal bacteria at the early onset of type 2 diabetes: molecular mechanisms and probiotic treatment (2011, neutral): “Hence, obesity could be transferred by the intestinal microbiota (Backhed et al, 2004, 2005; Ley et al, 2005, 2006; Turnbaugh et al, 2006, 2007).”
- A Metagenomic Approach to Characterization of the Vaginal Microbiome Signature in Pregnancy (2012, background): “, the NIH Road Map initiative known as the Human Microbiome Project (HMP)) will enable sequence-based comprehensive characterization of the adult human microbiota and theoretically allow for cataloguing of the microbiota into core guilds, which can be thereafter interrogated for their associations w”
- Scaling laws predict global microbial diversity (2016, methodology): “More detail on HMP sequencing and sampling protocols can be found at hmpdacc.org/micro_analysis/microbiome_analyses.php.”