Biology of posttraumatic stress disorder.

By R. Yehuda. Journal of Clinical Psychiatry, 2001

674 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/a0ee84aba6e21b9cd0cfd7dff8c7d0b10a8fe7fa

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

Citations in the corpus

The neurobiology of stress and development. (2007, background): “Depression among adults is often associated with reduced negative feedback regulation (e.g., Young et al. 1991), whereas PTSD appears to be associated with increased negative feedback (e.g., Yehuda 2000).”
What is Meant by Calling Emotions Basic (2011, background): “While there is not much evidence about how such experiences would modify facial expressions, the research on posttraumatic stress disorder (PTSD) suggests that the thresholds for the arousal of autonomic activity can be radically changed (Yehuda, 2001).”
Attention-deficit/hyperactivity disorder: diagnosis, lifespan, comorbidities, and neurobiology. (2007, background): “Exposure to violence may act through psychosocial adversity but may also lead to permanent brain changes, based on the impact of prolonged exposure of the developing brain to steroid hormones.(69) It is important to note that, although many studies provide powerful evidence for the importance of psy”
Neural Mechanisms of Extinction Learning and Retrieval (2008, background): “It has been known for some time that PTSD sufferers have reduced circulating levels of cortisol (Yehuda, 2001), suggesting that corticosteroids may have a protective effect.”
Child Maltreatment and Later Cognitive Functioning: A Systematic Review (2013, background): “According to the studies assessed in this review, the cognitive functions most commonly impaired in individuals with PTSD include (a) memory (to a greater extent in terms of immediate retrieval of verbal and visual information; to a lesser extent, in terms of non-immediate retrieval); (b) attention,”
Psychological stress and the human immune system: a meta-analytic study of 30 years of inquiry. (2004, background): “The next largest group of studies in this area examined immune responses to disasters, which may have different neuroendocrine consequences than loss; whereas loss is generally associated with increases in cortisol, trauma may be associated with decreases in cortisol (Yehuda, 2001;Yehuda, McFarlane,”
The role of childhood trauma in the neurobiology of mood and anxiety disorders: preclinical and clinical studies. (2001, result): “These findings are opposite to findings in Vietnam veterans and Holocaust survivors with PTSD (Yehuda 2000).”
The role of FKBP5, a co-chaperone of the glucocorticoid receptor in the pathogenesis and therapy of affective and anxiety disorders. (2009, background): “As described above, exposure to traumaand stress increaseHPA-axis activity, and PTSD has been associated with long-lasting alterations in HPA-axis reactivity (Yehuda, 2001; Yehuda et al., 1991) and specifically higher glucocorticoid receptor (GR) sensitivity (Yehuda et al., 2004a,b).”
When not enough is too much: the role of insufficient glucocorticoid signaling in the pathophysiology of stress-related disorders. (2011, background): “Decreased plasma, salivary, and urinary cortisol concentrations have also been reported in subjects suffering from posttraumatic stress disorder (PTSD), whether the syndrome developed as a result of combat exposure or a natural disaster, such as an earthquake, or following sexual and/or physical abu”