The role of FKBP5, a co-chaperone of the glucocorticoid receptor in the pathogenesis and therapy of affective and anxiety disorders.

By Elisabeth B. Binder. Psychoneuroendocrinology, 2009

921 citations recorded by the source corpus.

Subfields: Behavioral Neuroscience, Endocrinology, Diabetes and Metabolism, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/81fd26c6e7d44e96f8d3597b28975280a13438c2

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Behavioral Neuroscience

1. Christine Marcelle Heim
2. Elisabeth B. Binder
3. K. Ressler
4. C. Nemeroff

In Endocrinology, Diabetes and Metabolism

1. Christine Marcelle Heim
2. Elisabeth B. Binder

In Molecular Biology

1. Christine Marcelle Heim
2. Elisabeth B. Binder

Citations in the corpus

• Inflammation in Fear- and Anxiety-Based Disorders: PTSD, GAD, and Beyond (2017, background): “…is induced by glucocorticoids, thus forming an ultrashort intracellular negative-feedback loop for GR activity in response to stressor exposure (Vermeer et al, 2003), such that increased expression of FKBP5 following GR activation leads to the subsequent reduction in GR sensitivity (Binder, 2009).”
• Current research trends in early life stress and depression: review of human studies on sensitive periods, gene-environment interactions, and epigenetics. (2012, positive): “negative feedback of the stress hormone system (Binder 2009).”