Biomechanical and molecular regulation of bone remodeling.

By A. Robling, Alesha B. Castillo, C. Turner. Annual Review of Biomedical Engineering, 2006

1,331 citations recorded by the source corpus.

Subfields: Molecular Biology, Orthopedics and Sports Medicine, Rheumatology

View Paper: https://www.semanticscholar.org/paper/a04ca4ba84ca095196de1767b3c11aff31d40516

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Citations in the corpus

Characterization of Bone and Bone-Based Graft Materials Using FTIR Spectroscopy (2012, background): “The bone turnover or remodelling, that consists on the resorption, www.intechopen.com Infrared Spectroscopy – Life and Biomedical Sciences 316 followed by the replacement of bone with little change in shape, acts as a dynamic response to multiple local and systemic factors (Robling et al., 2006).”
Sclerostin Mediates Bone Response to Mechanical Unloading Through Antagonizing Wnt/β‐Catenin Signaling (2009, background): “chanical stress on bone) leads to significant bone loss, as evidenced by disuse osteoporosis, which is a critical issue for bedridden patients and astronauts.((2,3)) Although rapid”
Nature’s hierarchical materials (2007, background): “Some principal results on the mechanobiological aspects of bone remodeling [279,280] as investigated using in vivo, in vitro and in silico models are reviewed in the following sections.”
Biology of Bone Tissue: Structure, Function, and Factors That Influence Bone Cells (2015, background): “Bone remodeling is a highly complex cycle that is achieved by the concerted actions of osteoblasts, osteocytes, osteoclasts, and bone lining cells [3].”
Integrins and extracellular matrix in mechanotransduction. (2010, background): “Bone formation and turnover are regulated by weight-bearing exercise such that bone density increases under higher loads and decreases under lower loading (Robling et al. 2006).”
Bone deep: variation in stable isotope ratios and histomorphometric measurements of bone remodelling within adult humans (2017, background): “Bone remodelling occurs throughout the whole human lifespan (Burr and Allen, 2014; Katsimbri, 2017; Robling et al., 2006; Peacock, 2010) as osteoclasts resorb old tissue and osteoblasts produce new tissue (Robling et al., 2008; Miszkiewicz and Mahoney, 2016).”
Silk fibroin as biomaterial for bone tissue engineering. (2016, background): “Osteoblasts are derived from mesenchymal stem cells (MSCs) located in the bone marrow and differentiate towards the osteogenic lineage [21].”
Calcium metabolism in health and disease. (2010, background): “Bone Calcium Remodeling Bone continuously remodels by coordinated cellular mechanisms to adapt its strength to the changing needs of growth and physical exercise (26).”
Effects of obesity on bone metabolism (2011, background): “Therefore, mechanical loading conferred by body weight is part of the assumption that has led to widespread belief that obesity may prevent bone loss and osteoporosis [59-63].”