The neurobiology of consolidations, or, how stable is the engram?

By Y. Dudai. 2004

1,676 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Cognitive Neuroscience

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In Cognitive Neuroscience

Citations in the corpus

Short-term plasticity as cause–effect hypothesis testing in distal reward learning (2014, background): “The model can also be seen as a high-level abstraction of memory consolidation (McGaugh, 2000; Bailey et al, 2000; Lamprecht and LeDoux, 2004; Dudai, 2004; Mayford et al, 2012) under the effect of delayed dopaminergic activity (Jay, 2003), particularly at the synaptic level as the transition from ea”
About sleep's role in memory. (2013, background): “Indeed, the destabilization of long-term memories after reactivation might be highly adaptive because it presents the opportunity to update memories with respect to new experiences (330, 513, 718, 957).”
Effects of Prior Knowledge on Memory: Implications for Education. (2016, background): “…refers to a process during which new and initially labile memories (presumably formed by the hippocampus) are transformed into more stable representations that become integrated into the pre-existing knowledge network represented across the neocortex (Dudai, 2004; Dudai & Morris, 2013).”
The Formation of Recent and Remote Memory Is Associated with Time-Dependent Formation of Dendritic Spines in the Hippocampus and Anterior Cingulate Cortex (2009, background): “Memory traces are not definitively fixed at the time of encoding but undergo a gradual process of stabilization and consolidation (Dudai, 2004; Squire et al., 2004).”
Astrocyte-neuron lactate transport is required for long-term memory formation (2011, positive): “While short-term memories require posttranslational modifications, the consolidation, or stabilization of long-termmemories depends upon the activation of a gene cascade and downstream modifications in neurons that store the acquired information (Dudai, 2004; Kandel, 2001; Klann and Sweatt, 2008).”
Contributions of the basal ganglia and functionally related brain structures to motor learning. (2009, positive): “Although still conjectural in humans, it is widely accepted that, during learning and immediately after, physiological and structural synaptic changes take place in the nervous system in order for the memory trace to persist and be consolidated [26,27].”
Cdc42-Dependent Forgetting Regulates Repetition Effect in Prolonging Memory Retention. (2016, background): “In animal models, studies of repetition effects on memory have focused on mechanisms underlying so-called memory consolidation (Dudai, 2004; Kandel, 2001; McGaugh, 2000).”
Memory consolidation. (2015, background): “As noted by Dudai (2004), the susceptibility to corruption of a retrieved memory "might be the price paid for modifiability" (p. 75). If the reactivated trace is susceptible only to agents such as anisomycin, which is not a drug that is encountered on a regular basis, then the price for modifiabilit”
Replay of rule-learning related neural patterns in the prefrontal cortex during sleep (2009, background): “The system consolidation theory views the interaction between hippocampus and neocortex as being instrumental for thi”
Remembered experiences and revisit intentions: A longitudinal study of safari park visitors (2016, background): “…memory does not come about as a result of decay, but rather, more complex phenomena (Jenkins and Dallenbach, 1924; McGeoch, 1932), such as those explained via the psychological theories of interference (Underwood, 1957; Underwood and Postman, 1960) and consolidation (Dudai, 2004; McGaugh, 2000).”
Mental number line training in children with developmental dyscalculia (2011, background): “Consolidation is a category of processes that stabilize a memory trace after the initial acquisition (Dudai, 2004).”
Memory engrams: Recalling the past and imagining the future (2020, background): “M emory is the ability to use the past in service of the present or future (1, 2).”
The organization of recent and remote memories (2005, background): “Consolidation involves reorganization at both the synaptic and system level”
ReviewMemory Consolidation in Sleep: Dream or Reality (2004, background): “By contrast, several other TCAs, hours and long-term processes that could stretch for including doxepin, desipramine, nortriptyline, amox- years or a lifetime (Squire, 1987; McGaugh, 2000; Eichapine, protriptyline, maprotiline, and chlorimipramine enbaum and Cohen, 2001; Dudai, 1989, 2004).”