Microbial influences in inflammatory bowel diseases.

By R. Sartor. Gastroenterology, 2008

1,975 citations recorded by the source corpus.

Subfields: Genetics, Infectious Diseases, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/9fecd3dcd5c41f82e2ecb891f18872dad07937bc

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Genetics

1. J. Turner
2. B. B. Finlay
3. Pankaj Agarwal
4. Guanghui Hu
5. C. Bevins
6. I. Sekirov
7. Nita H. Salzman
8. F. Powrie

In Infectious Diseases

1. J. Turner
2. Guanghui Hu
3. Pankaj Agarwal
4. C. Bevins
5. B. B. Finlay
6. Nita H. Salzman
7. F. Powrie
8. K. Maloy

In Molecular Biology

1. Dan R. Littman
2. K. Honda
3. J. Turner
4. W. D. de Vos
5. H. Smidt
6. Pankaj Agarwal
7. Guanghui Hu
8. C. Bevins

Citations in the corpus

• Intestinal microbiota in human health and disease: the impact of probiotics (2011, background): “For both CD and UC, the exact aetiology is still not clear, however, it is has been suggested that an aberrant immune response directed against intestinal microbial antigens is involved (Hansen et al. 2010; Sartor 2008; Sokol and Seksik 2010).”
• Human Disease-Drug Network Based on Genomic Expression Profiles (2009, result): “This seemingly surprising connection is supported by emerging evidence that Crohn’s disease has potential infectious causes [29,30].”
• Alteration of Gut Microbiota in Inflammatory Bowel Disease (IBD): Cause or Consequence? IBD Treatment Targeting the Gut Microbiome (2019, background): “More in-depth studies conducted in UC and CD patients have shown a clear reduction in Firmicutes (especially Clostridium groups) and an increase in Proteobacteria [28,84,85], alongside a significant decrease of many other beneficial bacterial species from the genera Bacteriodes, Lactobacillus, and E”
• High-throughput clone library analysis of the mucosa-associated microbiota reveals dysbiosis and differences between inflamed and non-inflamed regions of the intestine in inflammatory bowel disease (2011, background): “Faecal stream diversion induces remission in CD [13], animal models of colitis require the presence of gut bacteria to initiate inflammation (reviewed in [14]), an increased mucosal bacterial load is observed in IBD patients [15,16], genome-wide IBD association studies have identified polymorphisms ”
• Disease phenotype and genotype are associated with shifts in intestinal-associated microbiota in inflammatory bowel diseases (2010, result): “We confirmed that decreases in the relative frequencies of Clostridial XIVa and IV taxa and increases in Proteobacteria taxa were observed in CD specimens compared to control specimens [3,7,8].”
• Gut microbiome analysis as a tool towards targeted non-invasive biomarkers for early hepatocellular carcinoma (2018, background): “…our cohort, but likely suggested the overgrowth of various harmful bacteria or archaea in patients with HCC. Gut microbial alteration in chronic diseases including T2D, 17 inflammatory bowel diseases, 37 38 colorectal adenoma–carcinoma sequence 32 and liver cirrhosis 23 is unique for each disease.”
• Induction of intestinal Th17 cells by segmented filamentous bacteria (2009, background): “There is evidence that the course of certain autoimmune diseases in humans and in animal models can be altered by treatment with antibiotics and probiotics and by restricting the complexity of the microbiota (O’Dell et al., 2006; Sartor, 2008).”
• Dextran Sodium Sulphate Colitis Mouse Model: Traps and Tricks (2012, background): “Hindawi Publishing Corporation Journal of Biomedicine and Biotechnology Volume 2012, Article ID 718617, 13 pages doi:10.1155/2012/718617 Review Article Dextran Sodium Sulphate Colitis Mouse Model: Traps and Tricks Martina Perše and Anton Cerar Institute of Pathology, Medical Experimental Centre,…”
• Impact of the Gut Microbiota on Intestinal Immunity Mediated by Tryptophan Metabolism (2018, background): “Along with reduced CYP11A1 expression (Coste et al., 2007) and decreased glucocorticoid production (Huang et al., 2014), disorders of intestinal steroidogenesis have been associated with IBD.”
• Dietary factors and low-grade inflammation in relation to overweight and obesity (2011, positive): “The microbiota composition and the related local intestinal metabolism undergoes significant changes in various disease states that are characterised by chronic inflammation, such as inflammatory bowel disease((823)), colorectal cancer and obesity((824,825)).”
• Intestinal mucosal barrier function in health and disease (2009, result): “Other data also support important roles for luminal material, particularly microorganisms and their products, in mucosal immune regulatio”