Endothelial/Pericyte Interactions

By A. Armulik, A. Abramsson, C. Betsholtz. Circulation Research, 2005

1,984 citations recorded by the source corpus.

Subfields: Cancer Research, Immunology and Allergy, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/9f6676dd97400eeac6e4a11e29753a28d694814a

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Citations in the corpus

Pericytes control key neurovascular functions and neuronal phenotype in the adult brain and during brain aging (2010, methodology): “Quantitative image analysis, including desmin-positive pericyte coverage, NG2-positive pericyte number, lectin-positive capillary length, CD31-positive capillary length, fluorescent intensity analysis of extravascular IgG and fibrin accumulation, aquaporin-4-positive or a-syntrophin-positive astrocy”
Fate tracing reveals the pericyte and not epithelial origin of myofibroblasts in kidney fibrosis. (2010, background): “Since pericytes are known in other tissues to supply endothelial cell survival factors such as angiopoietins, subsequent differentiation of these cells into myofibroblasts with migration away from vasculature may also lead to endothelial cell death and capillary rarefaction.(55) Chronic kidney disea”
The blood-brain barrier: an engineering perspective (2013, background): “An in vitro model of the human BBB should exhibit restricted paracellular transport (TEER = 1 k cm2, Psucrose 10−7 cm s−1), BMECs with the morphology and characteristics typical of the BBB, expression of BBB-specific markers and transporters, and be readily available, convenient to use, and reprod”
The blood-brain barrier in health and chronic neurodegenerative disorders. (2008, positive): “In addition to providing mechanical stability, pericytes predominantly influence vessel stability by matrix deposition and by the releae and activation of signals that promote BEC differentiation and quiescence (Armulik et al., 2005).”
Accessories to the crime: functions of cells recruited to the tumor microenvironment. (2012, positive): “Certainly the most well-established extrinsic modulator of cancer cell (and thus tumor) growth is lesional neovascularization (Folkman, 1974), involving the tubeforming endothelial cells and their supporting pericytes that comprise the angiogenic vasculature (Armulik et al., 2005).”
Molecular regulation of angiogenesis and lymphangiogenesis (2007, background): “Furthermore, the physical contact between ECs and pericytes is thought to induce a quiescent, non-sprouting phenotyp”
Pericytes: developmental, physiological, and pathological perspectives, problems, and promises. (2011, background): “Several recent reviews provide lists of molecular markers for pericytes (Armulik et al., 2005; Dı́az-Flores et al., 2009; Krueger and Bechmann, 2010) (examples shown in Figure 2).”
The brain tumor microenvironment (2011, background): “that is required for vessel stabilization (Armulik et al., 2005).”