Salmonella pathogenicity island 2-dependent evasion of the phagocyte NADPH oxidase.

By A. Vázquez-Torres, Yisheng Xu, J. Jones-Carson, D. Holden, Scott Lucia, M. Dinauer, P. Mastroeni, F. Fang. Science, 2000

623 citations recorded by the source corpus.

Subfields: Endocrinology, Food Science

View Paper: https://www.semanticscholar.org/paper/9f4d7daf5d8b0ce50e6f922adae59a2f39044dd4

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Endocrinology

1. B. B. Finlay
2. James J. Collins
3. P. Cossart
4. J. Galán
5. A. Kettle
6. C. Winterbourn

In Food Science

1. B. B. Finlay
2. James J. Collins
3. P. Cossart
4. J. Galán

Citations in the corpus

• Neutrophils to the ROScue: Mechanisms of NADPH Oxidase Activation and Bacterial Resistance (2017, background): “S. typhimurium uses factors encoded within the SPI-2 pathogencity island to exclude cytb558 from the phagosomal membrane of macrophages (Vazquez-Torres et al., 2000; Gallois et al., 2001).”
• Anti-immunology: evasion of the host immune system by bacterial and viral pathogens. (2006, background): “Similarly, Salmonella Spi2 is also required to evade phagocyte NADPH oxidase-mediated killing (Vazquez-Torres et al., 2000).”
• Macrophage Polarization in Bacterial Infections (2008, background): “typhimurium SPI-2 encodes mediators that inhibit phagosome relocalization of NADPH oxidase, thus inhibiting the oxidative microbicidal activity of macrophages (46).”
• Antimicrobial reactive oxygen and nitrogen species: concepts and controversies (2004, background): “enterica is phagocytosed but subsequently translocates microbial proteins to the macrophage cytosol, which interfere with the delivery of ROS and RNS into the phagocytic vacuol”
• Pathogenicity Islands in Bacterial Pathogenesis (2004, background): “Is has been reported that SPI-2 function prevents the colocalization of the phagocyte oxidase (357) as well as the inducible nitric oxide synthase (50) with the SCV.”
• How bacterial pathogens colonize their hosts and invade deeper tissues. (2015, background): “responsible for the production of bactericidal compounds that normally kill intracellular 352 bacteria [66].”
• How antibiotics kill bacteria: from targets to networks (2010, background): “In addition, considering bacteria have developed mechanisms to avoid ROS produced by phagocytes of the immune syste”
• Reactive Oxygen Species and Neutrophil Function. (2016, background): “For example Salmonella secrete a protein that prevents the assembly and activation of NOX2 (79).”
• Salmonella interactions with host cells: type III secretion at work. (2001, background): “2000) and the avoidance of NADPH oxidase–dependent killing (Vazquez-Torres et al. 2000).”