Tofacitinib (CP-690,550) in combination with methotrexate in patients with active rheumatoid arthritis with an inadequate response to tumour necrosis factor inhibitors: a randomised phase 3 trial.
By G. Burmester, R. Blanco, C. Charles-Schoeman, J. Wollenhaupt, C. Zerbini, B. Benda, D. Gruben, G. Wallenstein, S. Krishnaswami, S. Zwillich and 4 more. The Lancet, 2013
644 citations recorded by the source corpus.
Subfields: Hematology, Rheumatology
View Paper: https://www.semanticscholar.org/paper/9dbcbdb98ff9ed97d6da7c0036b5b0405e378705
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Citations in the corpus
- The JAK-STAT Pathway: Impact on Human Disease and Therapeutic Intervention (2015, background): “Patients with disease refractory to both conventional and biologic diseasemodifying antirheumatic drugs (DMARDs) were responsive to tofacitinib (59), and tofacitinib halted radiographic progression of RA (60, 61).”