Putting tumours in context

By Mina J. Bissell, Derek C. Radisky. Nature Reviews. Cancer, 2001

2,104 citations recorded by the source corpus.

Subfields: Immunology, Immunology and Allergy

View Paper: https://www.semanticscholar.org/paper/9bdd522637267c202addde3cb073116c86e052ea

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Citations in the corpus

Anoikis: an emerging hallmark in health and diseases (2012, positive): “The role of ECM as anoikis suppressor is well established [1,49] and several integrins (α1β1, α2β1, α3β1, α5β1, α6β1, α6β4, αvβ3) have a profound impact on cell survival [2,44,50] in both normal or neoplastic cells [2,51,52].”
Extracellular matrix: a dynamic niche component during cancer progression (2012, positive): “The concept that local microenvironments, or niches, play an impor tant role in regulating cell behavior, which is one of the central themes in classical embryology, has become increasingly ac cepted in cancer biology (Bissell and Radisky, 2001; Wiseman and Werb, 2002; Bissell and Labarge, 2005).”
Pancreatic cancer biology and genetics (2002, result): “These concepts are consistent with recent studies showing that cancers 'programme' an oncogenic stroma that, in turn, contributes to tumour growth through paracrine signalling, angiogenesis and protection from immune attac”
Stromal-epithelial interactions in aging and cancer: senescent fibroblasts alter epithelial cell differentiation (2004, background): “Because loss of differentiation is a hallmark of cancer progression (Bissell and Radisky, 2001; Petersen et al., 1998), this finding suggested that senescent fibroblasts might promote age-related cancer in part by altering epithelial differentiation.”
Depletion of Carcinoma-Associated Fibroblasts and Fibrosis Induces Immunosuppression and Accelerates Pancreas Cancer with Diminished Survival (2014, neutral): “The desmoplastic reaction is thought to represent a host defense mechanism, similar to wound healing and tissue regeneration, to repair or hopefully impede the conversion of a neoplastic lesion into invasive carcinoma (Bissell and Radisky, 2001; Dvorak, 1986; Lu et al., 2012).”
The role of apoptosis in creating and maintaining luminal space within normal and oncogene-expressing mammary acini. (2002, background): “Subsequently, the presence of apoptotic cells in and in the control of cell proliferation and cell survival the lumen has been noted in several other in vitro spher(Bissell and Radisky, 2001).”