Altered gene expression of brain-derived neurotrophic factor and receptor tyrosine kinase B in postmortem brain of suicide subjects.

By Yogesh Kumar Dwivedi, H. Rizavi, R. Conley, R. Roberts, C. Tamminga, G. Pandey. Archives of General Psychiatry, 2003

867 citations recorded by the source corpus.

Subfields: Biological Psychiatry, Cellular and Molecular Neuroscience, Developmental Neuroscience

View Paper: https://www.semanticscholar.org/paper/9ba8b07dd6a66098b2469cb18608ddf2efd22165

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Biological Psychiatry

1. Wayne C. Drevets
2. R. Duman
3. Husseini K. Manji
4. L. Monteggia
5. H. Schmidt
6. Anita E. Autry
7. Dennis S. Charney
8. Andrew H. Miller

In Cellular and Molecular Neuroscience

1. L. Monteggia
2. R. Duman
3. H. Schmidt
4. Dennis S. Charney
5. Anita E. Autry
6. Husseini K. Manji
7. Wayne C. Drevets
8. Harry B. M. Uylings

In Developmental Neuroscience

1. H. Schmidt
2. Dennis S. Charney
3. L. Monteggia
4. R. Duman
5. Husseini K. Manji
6. Wayne C. Drevets
7. Anita E. Autry
8. A. Kramer

Citations in the corpus

• Neurobiology of suicidal behaviour (2003, background): “Especially younger patients had a high prevalence of hyperintensities in the deep white matter of the parietal lobe and past suicide attempts (Ehrlich et al. 2003).”
• A review of depression and suicide risk assessment using speech analysis (2015, background): “BDNF abnormalities have also been associated with suicidal behaviours (Costanza et al., 2014; Dwivedi et al., 2003).”
• The role of neurotrophic factors in adult hippocampal neurogenesis, antidepressant treatments and animal models of depressive-like behavior (2007, background): “mRNA is decreased in postmortem hippocampal tissue from depressed suicide victims relative to matched controls (Chen et al., 2001b; Dwivedi et al., 2003b; Karege et al., 2005b).”
• Brain-Derived Neurotrophic Factor: A Key Molecule for Memory in the Healthy and the Pathological Brain (2019, neutral): “, 2015) and the prefrontal cortex (Dwivedi et al., 2003).”
• Brain-Derived Neurotrophic Factor and Neuropsychiatric Disorders (2012, background): “In humans with MDD, this brain region is also decreased in volume, which is correlated with decreased BDNF and TrkB levels (Dwivedi et al., 2003; Castrén, 2004; Pandey et al., 2008).”
• Cellular changes in the postmortem hippocampus in major depression. (2004, background): “In the Dwivedi et al (2003) study, the decrease in expression of BDNF occurred regardless of antidepressant treatment.”
• Discovering Endophenotypes for Major Depression (2004, background): “Decreased levels of CREB, BDNF, and the TrkB receptor have been reported in suicide victims (Odagaki et al, 2001; Dwivedi et al, 2003).”
• Enrichment Effects on Adult Cognitive Development (2008, background): “…evidence of downregulation of glucocorticoid receptors in patients who had mood disorders prior to death (Webster, Knable, O’Grady, Orthman, & Weickert, 2002) and of reduced expression of brain-derived neurotrophic factor and its receptor in persons who committed suicide (Dwivedi et al., 2003).”