Histone H3 lysine 9 methylation and HP1gamma are associated with transcription elongation through mammalian chromatin.

By C. Vakoc, S. Mandat, B. Olenchock, G. Blobel. Molecules and Cells, 2005

738 citations recorded by the source corpus.

Subfields: Molecular Biology

View Paper: https://www.semanticscholar.org/paper/9b39a7356294538cb9b6d7fd4d8c4b799a8ec63a

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In Molecular Biology

1. Yi Zhang
2. Yang Shi
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7. Miho M. Suzuki
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Citations in the corpus

• CREB up-regulates long non-coding RNA, HULC expression through interaction with microRNA-372 in liver cancer (2010, background): “As for the heterochromatin marker Dimethyl-H3K9, which serves as a signal for chromatin silencing by recruiting the HP1 protein (heterochromatin protein 1) and is mutually exclusive with H3-K9 acetylation (25), it was scored lower in R6 and R7 regions in cancer cells (Figure 2G and H).”
• DNA methylation landscapes: provocative insights from epigenomics (2008, background): “In addition, the histone deacetylation that is triggered by methylation of histone H3K36 within yeast transcription units is required to prevent spurious intragenic transcriptional initiatio”
• Reversal of histone lysine trimethylation by the JMJD2 family of histone demethylases. (2006, background): “However, H3-K9Me3 in the gene-coding regions is associated with transcriptional elongation (Vakoc et al., 2005), while, H3-K36Me2/3 plays an important role in suppressing inappropriate transcription within the body of genes (Carrozza et al.”
• Integrative epigenomic mapping defines four main chromatin states in Arabidopsis (2011, background): “However, association with the transcribed regions of some active genes has been reported in mammals (Vakoc et al, 2005, 2006; Squazzo et al, 2006).”
• Differential chromatin marking of introns and expressed exons by H3K36me3 (2009, background): “Studies on small gene sets also detected H3K9me3 in the bodies of actively transcribed gene”
• The diverse functions of histone lysine methylation (2005, background): “A recent study has challenged the generality of the association between H3-K9 methylation and gene silencin”
• Child health, developmental plasticity, and epigenetic programming. (2011, background): “Indeed, marks that were originally thought to be “active” can be found within silent genes and vice versa; H3K9me3 is found both in silent heterochromatin and at some active genes (90).”