The ins and outs of sphingolipid synthesis.

By A. Futerman, Howard Riezman. 2005

330 citations recorded by the source corpus.

Subfields: Cell Biology, Molecular Biology

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cell Biology

1. Michal Levy
2. G. Meer
3. S. Alexander
4. J. Min
5. Hannah Alexander
6. A. Futerman
7. A. Mesika

In Molecular Biology

1. Michal Levy
2. S. Alexander
3. Hannah Alexander
4. A. Mesika
5. J. Min
6. M. Sivaguru
7. P. V. Van Veldhoven
8. A. Futerman

Citations in the corpus

• Mammalian Ceramide Synthases (2010, background): “The biochemical pathways of ceramide and SL synthesis are well established and most of the enzymes have been identified and cloned (3).”
• Roles of bioactive sphingolipids in cancer biology and therapeutics. (2008, neutral): “16.1) (Futerman and Hannun, 2004; Futerman and Riezman, 2005).”
• Differential expression of (dihydro)ceramide synthases in mouse brain: oligodendrocyte-specific expression of CerS2/Lass2 (2008, neutral): “Dihydroceramide is then converted to ceramide by dihydroceramide desaturase (Futerman and Riezman 2005).”
• (Dihydro)ceramide Synthase 1–Regulated Sensitivity to Cisplatin Is Associated with the Activation of p38 Mitogen-Activated Protein Kinase and Is Abrogated by Sphingosine Kinase 1 (2007, background): “Dihydroceramide Synthase (CerS) Enzymes Six genes encoding different isoforms of mammalian dihydroceramide synthase have been identified based on homology to the yeast LAG1 gene (19, 21, 38).”
• Membrane lipids: where they are and how they behave (2008, background): “The mammalian Golgi specializes in sphingolipid synthesis, and produces SM, GlcCer, lactosylceramide (LacCer) and higher-order GSL”
• Membrane Lipid Composition: Effect on Membrane and Organelle Structure, Function and Compartmentalization and Therapeutic Avenues (2019, background): “Mammalian Golgi is the main producer of SL: SM, GlcCer, lactosylceramide (LacCer) and higher-order GSLs, whose final destination is the PM [33].”
• Sorafenib and Vorinostat Kill Colon Cancer Cells by CD95-Dependent and -Independent Mechanisms (2009, background): “The six known ceramide synthase genes (LASS) are localized in the ER, and different LASS proteins have been noted to generate ceramide forms of different chain lengths, LASS5 and LASS6 being most closely linked to the generation of C14 and C16 dihydro ceramide (Ogretmen and Hannun, 2004; Futerman an”