Antigen-specific memory B cell development.

By L. McHeyzer-Williams, M. McHeyzer-Williams. Annual Review of Immunology, 2005

762 citations recorded by the source corpus.

Subfields: Immunology

View Paper: https://www.semanticscholar.org/paper/98987c11799b851671a95974c2cae96e70126b36

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Immunology

1. Bali Pulendran
2. Rafi Ahmed
3. M. Stanley
4. Y. Hayakawa
5. D. Irvine
6. M. Smyth
7. J. Moon
8. E. Wherry

Citations in the corpus

• Multiple layers of B cell memory with different effector functions (2009, background): “At the end of the GC reaction, some B cells that have acquired a memory phenotype remain in the organism, ready to respond to a new encounter with the immunizing antigen, whereas others have differentiated into short- and long-lived plasmocyte”
• Translating innate immunity into immunological memory: implications for vaccine development. (2006, background): “…like germinal centers and plasma foci represent the sites where somatic hypermutation of immunoglobulin genes in developing memory B cells and the generation of short-lived antibody-forming cells occur, respectively (Ahmed and Gray, 1996; McHeyzer-Williams and McHeyzer-Williams, 2005).”
• Enhancing humoral responses to a malaria antigen with nanoparticle vaccines that expand Tfh cells and promote germinal center induction (2012, background): “Durable and high-affinity humoral responses elicited by ICMVs suggest that NP vaccines may effectively stimulate formation of GCs, where activated B cells proliferate, undergo immunoglobulin isotype-switching and somatic hypermutation, and eventually form memory B cells that can rapidly differentiat”
• CD27 Dissects Mature NK Cells into Two Subsets with Distinct Responsiveness and Migratory Capacity1 (2006, background): “It has been recognized that there is clear, but lineage distinct, correlation of CD27 expression with lymphocyte differentiation (30, 41, 42).”
• Immune responses to human papillomavirus. (2006, background): “T cell help is crucial for class witching, generating different antibody classes and isotypes, nd developing antigen-specific memory B cells [3].”
• FOLLICULAR HELPER T CELLS: LINEAGE AND LOCATION (2009, background): “Developmental progression in antigen-specific PCs and GC B cells both involve the switch to downstream antibody isotypes (McHeyzer-Williams and McHeyzer-Williams, 2005) (depicted in Figure 2).”
• Mining human antibody repertoires (2010, background): “Post-GC B cells with affinity and isotype matured antibodies differentiate further into antibody secreting cells and memory B cells.(14) Antibody secreting cells can be divided into proliferating plasma blasts and fully differentiated plasma cells that no longer proliferate.”