High-resolution mapping and characterization of open chromatin across the genome.
By Alan P. Boyle, Sean Davis, H. Shulha, Paul S. Meltzer, Elliott H. Margulies, Zhiping Weng, Terrence S. Furey, Gregory E. Crawford. Cell, 2008
1,406 citations recorded by the source corpus.
Subfields: Molecular Biology
View Paper: https://www.semanticscholar.org/paper/987d10cb14e85af263e3172d1d0130003a52a63b
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In Molecular Biology
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Citations in the corpus
- Genome-wide mapping of HATs and HDACs reveals distinct functions in active and inactive genes (2009, background): “DNase HS sites were obtained from Boyle et al. (2008). (C) Correlation between HAT binding and gene expression levels.”
- Complexity of the Alternative Splicing Landscape in Plants[C][W][OPEN] (2013, background): “These studies suggest the functional significance of AS as a result of tandem acceptor in plants.”
- DNase-seq: a high-resolution technique for mapping active gene regulatory elements across the genome from mammalian cells (2010, positive): “…are enriched and either hybridized to tiled arrays or sequenced by using nextgeneration sequencing technologies such as Solexa/Illumina (Crawford et al. 2006; Sabo et al. 2006; ENCODE Project Consortium 2007; Xi et al. 2007; Boyle et al. 2008; Hesselberth et al. 2009; Shibata and Crawford 2009).”
- Dynamic reprogramming of chromatin accessibility during Drosophila embryo development (2011, background): “For this reason, delineation of DNaseI hypersensitive sites (DHSs) has proven to be a particularly powerful strategy for mapping regulatory DNA in eukaryotic cells [21-24], and recent advances in sequencing technology have enabled DHS mapping at genome scale [ 25-29 ].”
- DNA sequencing at 40: past, present and future (2017, positive): “Also around 2008, small laboratories that were early adopters of NGS developed ‘digital quantification’ methods for transcription-factor binding 117 , chromatin accessibility 118 and translation 119 .”
- Transcriptional enhancers: from properties to genome-wide predictions (2014, methodology): “This stereotypical chromatin structure is used for the identification of regulatory regions by enzymatic cleavage of accessible DNA using DNase I or micrococcal nuclease (MNase) coupled to deep sequencing (DNase-seq 60 (FIG.”