DNA sequencing at 40: past, present and future

By Jay Shendure, Shankar Balasubramanian, George M. Church, W. Gilbert, J. Rogers, J. Schloss, R. Waterston. 2017

948 citations recorded by the source corpus.

Subfields: Ecology, Molecular Biology

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Ecology

1. P. Hsu

In Molecular Biology

1. P. Hsu
2. M. Shokhirev
3. Jennifer Oki
4. Peter Lotfy
5. Silvana Konermann
6. Nicholas J. Brideau
7. Feng Zhang
8. Jennifer A. Doudna

Citations in the corpus

• CADD: predicting the deleteriousness of variants throughout the human genome (2018, neutral): “Human genome sequencing is now routine, and facilitates the ascertainment of millions of genetic variants within individuals, and hundreds of millions of variants across populations (1).”
• Long-read human genome sequencing and its applications (2020, neutral): “– Importantly, the technology’s throughput has allowed it to serve as an assay for digital readouts to investigate a myriad of biological phenomena, including chromatin accessibility, transcription factor occupancy, gene expression and RNA binding, among many other novel applications 2 .”
• Transcriptome engineering with RNA-targeting Type VI-D CRISPR effectors (2018, positive): “, 1995) to next-generation sequencing and single-cell studies (Shendure et al., 2017).”