Ceramide in the eukaryotic stress response.

By Yusuf A. Hannun, C. Luberto. Trends in Cell Biology, 2000

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Cathepsin D--many functions of one aspartic protease. (2008, background): “[116] Hannun YA, Luberto C.”
Lipid-induced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid-induced ceramide biosynthesis in mice. (2011, background): “31) and into sphingolipids involved in the general eukaryotic stress response (62).”
Molecular machinery for non-vesicular trafficking of ceramide (2003, background): “Ceramide, which can be produced in both anabolic and catabolic pathways, is a modulator of various cellular event”
Serine palmitoyltransferase, a key enzyme of sphingolipid metabolism. (2003, background): “In the past decade, sphingolipid metabolites have been revealed to modulate various cellular events including proliferation, differentiation, and apoptosis [3–5], and sphingolipids, along with cholesterol, have been shown to be required for the formation of detergent-resistant membrane microdomains ”