Metaplasticity: the plasticity of synaptic plasticity.

By Wickliffe C. Abraham, Mark F. Bear. 1996

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Citations in the corpus

A Comprehensive Survey of Continual Learning: Theory, Method and Application (2023, methodology): “of synaptic plasticity” [3], [4], [77], corresponding to the use of meta-learning [118], [185], [360]; and (4) inhibitory synapses for excited neurons to reduce the activity of other neurons [20], [54], [112], [178], which acts similarly to the binary mask for parameter allocation [375], [427].”
The temporal paradox of Hebbian learning and homeostatic plasticity (2017, background): “In neurobiology, forms of plasticity exist which seemingly enforce such limits or constraints through synaptic scaling in response to firing rate perturbations [13,14], or through stabilizing adjustments of the properties of plasticity in response to the recent synaptic history, a phenomenon known a”
Short-term plasticity as cause–effect hypothesis testing in distal reward learning (2014, background): “The consolidation process, in particular, expresses a meta-plasticity mechanism (Abraham and Bear, 1996; Abraham and Robins, 2005; Abraham, 2008), with similarities to the cascade model in Fusi et al (2005), because frequent short-term updates are preconditions for further longterm potentiation (Goe”
AMPA receptor trafficking at excitatory synapses. (2003, background): “Within the next decade it be- NMDA receptor function alter the threshold for inducing came clear that LTP is initiated by activation of postsyn- LTP/LTD, a phenomenon referred to as metaplasticity aptic NMDA-type receptors and a rise in postsynaptic (Abraham and Bear, 1996).”
Neuronal variability: noise or part of the signal? (2005, background): “R. Soc. Lond. B (2002) unattended points slightly left or right, but none changed”
LTP inhibits LTD in the hippocampus via regulation of GSK3beta. (2007, unknown): “The regulation of synaptic plasticity is further complicated by the involvement of mGluRs, which are involved in depotentiation (Bortolotto et al., 1994), LTD of baseline transmission (Bolshakov and Siegelbaum, 1994), heterosynaptic LTD (Daw et al., 2002) and metaplasticity (Abraham and Bear, 1996).”
Synaptic Mechanisms for Plasticity in Neocortex (2009, background): “A distinct class of plasticity is metaplasticity, that is, experience-dependent changes in synaptic plasticity rules themselves (Abraham & Bear 1996).”
Glia-derived D-serine controls NMDA receptor activity and synaptic memory. (2006, background): “transmission, also referred to as metaplasticity (Abraham and Bear, 1996).”
Synaptic Plasticity in Neural Networks Needs Homeostasis with a Fast Rate Detector (2013, background): “This finding is in contrast to most known homeostatic mechanisms that have experimentally been found to act on effective timescales of hours or days [20,29,36,37].”
The Self-Tuning Neuron: Synaptic Scaling of Excitatory Synapses (2008, background): “…Goaillard, 2006; Zhang and Linden, 2003), regulating inhibitory and/or excitatory synaptic strength (Turrigiano and Nelson, 2004) or synapse number (Kirov et al., 2004), or adjusting the ease with which other forms of plasticity can be induced (socalled “metaplasticity”; Abraham and Bear, 1996).”
STDP rule endowed with the BCM sliding threshold accounts for hippocampal heterosynaptic plasticity (2007, background): “Metaplasticity refers to the prior history of pre- or postsynaptic neural activity controlling the subsequent induction of synaptic plasticity at the stimulated input (Abraham and Bear, 1996).”