Sunlight and vitamin D for bone health and prevention of autoimmune diseases, cancers, and cardiovascular disease.

By M. F. Holick. American Journal of Clinical Nutrition, 2004

2,865 citations recorded by the source corpus.

Subfields: Behavioral Neuroscience, Nutrition and Dietetics, Pathology and Forensic Medicine

View Paper: https://www.semanticscholar.org/paper/95fc466cf5a42a73d5413659a9926d81f9a2ac40

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Behavioral Neuroscience

1. A. Ascherio
2. K. Munger
3. M. Wacker
4. A. Spiro
5. J. Buttriss
6. Yunhui Liu
7. Lei Zhang
8. K. Y. Forrest

In Nutrition and Dietetics

1. M. Wacker
2. A. Ascherio
3. K. Munger
4. M. F. Holick
5. K. Y. Forrest
6. W. Stuhldreher
7. C. Rosen
8. M. H. Murad

In Pathology and Forensic Medicine

1. M. F. Holick
2. M. Wacker
3. K. Munger
4. A. Ascherio
5. C. Rosen
6. K. Y. Forrest
7. W. Stuhldreher
8. M. H. Murad

Citations in the corpus

• UV Radiation and the Skin (2013, background): “Instead, the industry publicizes the health benefits of UV to its clients, emphasizing vitamin D production which is naturally made in the skin by the chemical conversion of 7-dehydrocholesterol into vitamin D3 (cholecalciferol) after UVB exposure [61–69].”
• Environmental risk factors for multiple sclerosis. Part II: Noninfectious factors (2007, background): “For most people, exposure to sunlight is their major source of vitamin D.(15) Ultraviolet B radiation (290–320nm) converts cutaneous 7-dehydrocholesterol to previtamin D3, which spontaneously isomerizes to vitamin D3.”
• The nonskeletal effects of vitamin D: an Endocrine Society scientific statement. (2012, background): “SMAD3, a transcription factor in the TGFpathway, has been found to complex with the SRC family members and the VDR, enhancing the coactivation process (28).”
• Vitamin D: An overview of vitamin D status and intake in Europe (2014, background): “For example, melanin efficiently absorbs UVB photons and people with increased skin melanin pigmentation (darker skin) require longer exposures to sunlight to make the same amount of vitamin D compared with light-skinned people (Holick 2004).”
• Vitamin D—Effects on Skeletal and Extraskeletal Health and the Need for Supplementation (2013, background): “In the 1930s, the fortification of milk, sodas, bread and even beer became popular [26]; however, after several cases of presumed vitamin D intoxication in infants in the 1950s in Great Britain [27] strict regulations limiting vitamin D fortification to only margarine were introduced in Europe [14,2”
• Prevalence of cardiovascular risk factors and the serum levels of 25-hydroxyvitamin D in the United States: data from the Third National Health and Nutrition Examination Survey. (2007, result): “Previous studies suggesting similar associations between low serum vitamin D levels and CVD risk factors were limited to subpopulations and small study samples.(3,22) Several plausible biological mechanisms that link vitamin D with CVD and CVD risk factors have been identified.”
• Vitamin D for Health: A Global Perspective (2013, neutral): “lumisterol) inactive on calcium metabolism are produced at times of prolonged exposure to solar UV-B radiation, thus preventing suninduced vitamin D intoxication.(7,8) Vitamin D3 is also sensitive to solar irradiation and is, thereby, inactivated to suprasterol 1 and 2 and to 5,6-trans-vitamin D3.”
• Prevalence and correlates of vitamin D deficiency in US adults. (2011, background): “However, due to its beneficial effects, the amounts of vitamin D needed for optimal health are probably higher than previously thought [2,23].”
• Serum 25-hydroxyvitamin D levels and risk of multiple sclerosis. (2006, background): “Physiological blood levels of 1,25dihydroxyvitamin D, however, are tightly regulated and are not measurably affected by exposure to sunlight or dietary vitamin D.(34) In contrast, circulating levels of 25hydroxyvitamin D are sensitive to both factors.”
• Potential interventions for novel coronavirus in China: A systematic review (2020, background): “deficiency, as do many elderly people, who have limited exposure to sunlight.(26) The COVID‐19 was first identified in Winter of 2019 and mostly affected middle‐aged to elderly people.”
• High prevalence of vitamin D inadequacy and implications for health. (2006, neutral): “ing the production of 1,25(OH) 2 D.(1,3)”