Potential interventions for novel coronavirus in China: A systematic review
By Lei Zhang, Yunhui Liu. Journal of Medical Virology, 2020
1,223 citations recorded by the source corpus.
An outbreak of a novel coronavirus (COVID‐19 or 2019‐CoV) infection has posed significant threats to international health and the economy. In the absence of treatment for this virus, there is an urgent need to find alternative methods to control the spread of disease. Here, we have conducted an online search for all treatment options related to coronavirus infections as well as some RNA‐virus infection and we have found that general treatments, coronavirus‐specific treatments, and antiviral treatments should be useful in fighting COVID‐19. We suggest that the nutritional status of each infected patient should be evaluated before the administration of general treatments and the current children's RNA‐virus vaccines including influenza vaccine should be immunized for uninfected people and health care workers. In addition, convalescent plasma should be given to COVID‐19 patients if it is available. In conclusion, we suggest that all the potential interventions be implemented to control the emerging COVID‐19 if the infection is uncontrollable.
Subfields: Infectious Diseases, Neurology
View Paper: https://www.semanticscholar.org/paper/4b008b19ceedf9e84836005db53c00ee56e5af8d
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Citations in the corpus
- Angiotensin receptor blockers as tentative SARS‐CoV‐2 therapeutics (2020, background): “The ultimate solution is, obviously, developing a SARS-CoV-2 vaccine (Patel et al., 2020; Zhang & Liu, 2020).”
- Fear and Practice Modifications among Dentists to Combat Novel Coronavirus Disease (COVID-19) Outbreak (2020, background): “Therefore, patients have to rely on supportive therapy such as vitamins A, C and D; chloroquine phosphate; and general healthcare until the body’s immune system can eradicate the infection [10].”
- ESPEN expert statements and practical guidance for nutritional management of individuals with SARS-CoV-2 infection (2020, neutral): “Part of the general nutritional approach for viral infections prevention is supplementation and/or adequate provision of vitamins to potentially reduce disease negative impact [15].”
- Novel 2019 coronavirus structure, mechanism of action, antiviral drug promises and rule out against its treatment (2020, background): “Other monoclonal, m396, CR3014 antibodies, neutralizing COVID-19 that may be an alternative for the treatment of more severe cases (Zhang & Liu, 2020).”
- Molecular immune pathogenesis and diagnosis of COVID-19 (2020, neutral): “Other monoclonal antibodies neutralizing SARS-CoV, such as m396, CR3014, could be an alternative for the treatment of SARS-CoV-2 [72].”
- COVID-19: Transmission, prevention, and potential therapeutic opportunities (2020, neutral): “Furthermore, m396, CR3014 [156], and Meplazumab (which is an anti-CD147 Mab [157], could be alternative monoclonal antibodies to be used against SARS-CoV-2 [153].”
- A Review of Coronavirus Disease-2019 (COVID-19) (2020, neutral): “Other drugs proposed for therapy arearbidol (an antiviral drug available in Russia and China), intravenous immunoglobulin, interferons, chloroquine and plasma of patients recovered from COVID-19 [29, 33, 34].”