MAP kinases in the immune response.

By C. Dong, R. Davis, R. Flavell. Annual Review of Immunology, 2002

1,795 citations recorded by the source corpus.

Subfields: Cancer Research, Immunology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/950dbc3e448d1b1bc724a1db9a213d70c04046ae

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cancer Research

1. W. Vanden Berghe
2. J. Pestka
3. G. Haegeman
4. K. De Bosscher
5. N. Perkins
6. Junying Yuan
7. D. Ofengeim

In Immunology

1. Angelika Schmidt
2. P. Krammer
3. W. Vanden Berghe
4. C. Rothlin
5. Nina Oberle
6. G. Haegeman
7. K. De Bosscher
8. G. Lemke

In Molecular Biology

1. DM Owens
2. P. Krammer
3. W. Vanden Berghe
4. T. Nürnberger
5. S. Keyse
6. L. Piater
7. G. Haegeman
8. K. De Bosscher

Citations in the corpus

• The interplay between the glucocorticoid receptor and nuclear factor-kappaB or activator protein-1: molecular mechanisms for gene repression. (2003, background): “Many proinflammatory cytokines, aberrantly up-regulated in chronic inflammatory diseases, require the concerted activation of NF- B and AP-1, which are positively controlled by MAPK cascades (708, 709).”
• MAPK phosphatases — regulating the immune response (2007, background): “In multicellular organisms, MAPKs are necessary for cellular differentiation, development, learning, memory and secretion of paracrine and autocrine factor”
• Flavonoids as anti-inflammatory agents: implications in cancer and cardiovascular disease (2009, background): “The three better characterized MAPKs are extracellular signal-regulated kinase 1 and 2 (Erk1/2), p38, and c-Jun N-terminal kinase (JNK) [103].”
• Molecular Mechanisms of Treg-Mediated T Cell Suppression (2012, background): “The AP-1 pathway is initiated by a MAPK cascade leading to activation of MAPKs, such as ERK, JNK, and p38 (Dong et al., 2002).”
• Innate immunity in plants and animals: striking similarities and obvious differences (2004, background): “As MAPKs also fulfill important regulatory functions during the initiation of innate immune responses in animal cells (93, 112), these elements add to the growing list of parallels in the molecular organization of innate immunity in both the plant and animal kingdoms (Fig.”
• TAM receptors are pleiotropic inhibitors of the innate immune response. (2007, background): “ERK1/2 and p38 MAP kinase, for example, are well-characterized effectors that are activated (phosphorylated) by TLR ligation (Dong et al., 2002).”