The interplay between the glucocorticoid receptor and nuclear factor-kappaB or activator protein-1: molecular mechanisms for gene repression.

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Integrating cell-signalling pathways with NF-κB and IKK function (2007, background): “Nuclear receptors (NRs) are transcription factors that are typically regulated by the binding of specific ligands, such as glucocorticoids, oestrogen, thyroid hormone and retinoic aci”
Molecular determinants of crosstalk between nuclear receptors and toll-like receptors. (2005, background): “…of signal-dependent gene expression, demonstrating that GR, PPARγ, and LXR repress overlapping but distinct subsets of inflammatory response genes, consistent with the large number of mechanisms that have been proposed for negative regulation by nuclear receptors (De Bosscher et al., 2003).”
Overview of Nomenclature of Nuclear Receptors (2006, background): “Indeed, the agonist-bound GR physically interacts with NF-(cid:2) B to block its transcriptional activity (McKay and Cidlowski, 1999; De Bosscher et al., 2003).”
Good cop, bad cop: the different faces of NF-κB (2006, background): “glucocorticoids are effected, at least in part, through repression of NF-kB transactivation (reviewed in De Bosscher et al.(52)).”