Sleep deprivation as a neurobiologic and physiologic stressor: Allostasis and allostatic load.

By Bruce S. McEwen. Metabolism: Clinical and Experimental, 2006

630 citations recorded by the source corpus.

Subfields: Behavioral Neuroscience, Endocrine and Autonomic Systems, Physiology

View Paper: https://www.semanticscholar.org/paper/926a2197606bf2e32495bb2b4340f10b898b751f

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In Behavioral Neuroscience

In Endocrine and Autonomic Systems

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Citations in the corpus

Allostatic load biomarkers of chronic stress and impact on health and cognition. (2010, background): “At first, prolonged secretion of the stress hormones epinephrine, norepinephrine, and cortisol (antagonized by dehydroepiandosterone) can falter in their ability to protect the distressed individual and instead begin to damage the brain and body (McEwen, 2006a).”
Sleep and immune function (2011, background): “In summary, chronic sleep deprivation can be seen as an unspecific state of chronic stress, which per se impacts immune functions and general health [27, 82, 83].”
Brain On Stress: Vulnerability and Plasticity of the Prefrontal Cortex Over the Life Course (2013, neutral): “Circadian disruption has sometimes been overlooked as a separate yet related phenomenon to sleep deprivation, which alters cognitive function, mood, and metabolism (McEwen, 2006).”
Consistent‐sufficient sleep predicts improvements in self‐regulatory performance and psychological strain (2011, background): “Moreover, much of the sleep and health research emphasizes sleep as an outcome of stress rather than a contributing factor, despite theoretical and empirical evidence of reciprocal causation (e.g. Armon, 2009; Benham, 2010; McEwen, 2006).”
Central effects of stress hormones in health and disease: Understanding the protective and damaging effects of stress and stress mediators. (2008, background): “Sleep deprivation produces an allostatic overload that can have deleterious consequences (McEwen, 2006, 2007).”
RESILIENCE TRAINING THAT CAN CHANGE THE BRAIN (2018, background): “For example, chronic sleep deprivation increases blood pressure, cortisol, insulin, and proinflammatory cytokines (McEwen, 2006).”