Glucagonocentric restructuring of diabetes: a pathophysiologic and therapeutic makeover.

By R. Unger, A. Cherrington. Journal of Clinical Investigation, 2012

648 citations recorded by the source corpus.

Subfields: Endocrinology, Diabetes and Metabolism, Molecular Biology, Surgery

View Paper: https://www.semanticscholar.org/paper/90d528e4ac3d60c27078b23f79eeac8913a7f39c

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Endocrinology, Diabetes and Metabolism

1. Gerald I. Shulman
2. V. Samuel
3. J. Gromada

In Molecular Biology

1. Gerald I. Shulman
2. V. Samuel
3. J. Gromada
4. Haiming Cao
5. Ralph DeFronzo
6. Max C. Petersen

In Surgery

1. Gerald I. Shulman
2. V. Samuel
3. J. Gromada
4. R. Medzhitov
5. M. Kotas

Citations in the corpus

• RNA Sequencing of Single Human Islet Cells Reveals Type 2 Diabetes Genes. (2016, background): “Hyperglucagonemia also plays a key role in the development and exacerbation of hyperglycemia in T2D (Unger and Cherrington, 2012).”
• The pathogenesis of insulin resistance: integrating signaling pathways and substrate flux. (2016, background): “Leptin clearly has pleiotropic effects on glucose metabolism, including reduction in food intake, which reduces ectopic lipid accumulation and improves hepatic and muscle insulin action in lipodystrophic individuals (63); reduction of glucagon secretion (104); neural regulation of hepatic glucose pr”
• Energy Metabolism in the Liver (2014, neutral): “In addition to insulin resistance, aberrant counterregu-latory hormone action in the liver also contributes to the progression of type 2 diabetes (264).”