Sox17 and β-catenin cooperate to regulate the transcription of endodermal genes

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Vertebrate Endoderm Development and Organ Formation (2009, background): “Crosstalk with other signaling pathways may account for the different activities, because Sox17 physically interacts with β-catenin to promote the transcription of some target genes, whereas it represses others (Sinner et al. 2004).”
Wnt signaling in the intestinal epithelium: from endoderm to cancer. (2005, background): “Indeed, Sinner et al. (2004) have proposed that in frogs, -catenin drives the expression of endoderm-specific target genes by physically associating with 878 GENES & DEVELOPMENT Sox17, an HMG box transcription factor, related to Tcfs.”
The many faces and functions of β‐catenin (2012, unknown): “…role in regulating hepatic metabolism and gluconeogenesis (Liu et al , 2011). b -Catenin has been reported to bind various other transcription factors (including Sox17 during vertebrate gastrulation) and augment transcription of their target genes (Sinner et al , 2004; Archbold et al , 2012).”